Would I prescribe steroid cream for a 31-year-old female with acute urticaria (hives) characterized by intermittent, itchy, raised, and red skin lesions on her arms, chest, and thighs?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 6, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Yes, I would prescribe a topical steroid cream for K.S.'s acute urticaria (hives). Specifically, I would recommend a medium-potency steroid such as triamcinolone 0.1% cream to be applied thinly to affected areas twice daily for 5-7 days. This should help reduce inflammation and relieve the itching. I would also suggest an oral antihistamine like cetirizine 10mg daily or diphenhydramine 25-50mg every 6 hours as needed for additional itch relief. The steroid cream works by suppressing the inflammatory response in the skin, while antihistamines block histamine receptors that trigger itching and swelling.

Key Considerations

  • K.S. should avoid hot showers, tight clothing, and vigorous scratching as these can worsen symptoms.
  • If symptoms persist beyond a week, worsen significantly, or if she develops any breathing difficulties or facial swelling, she should seek immediate medical attention as this could indicate progression to a more serious allergic reaction.

Treatment Rationale

According to the guidelines for evaluation and management of urticaria in adults and children 1, antihistamines are the mainstay of therapy, and over 40% of hospitalized patients with urticaria show a good response to antihistamines. Additionally, the British Association of Dermatologists' guidelines for the management of bullous pemphigoid 2012 1 suggest that topical steroids may be used as an adjunct to any other treatment or used as a monotherapy, either locally applied to lesions or all over the skin.

Monitoring and Follow-up

K.S. should be monitored for any changes in her symptoms, and if she experiences any worsening of symptoms or develops any new symptoms, she should seek medical attention promptly.

From the Research

Patient Evaluation

  • The patient, K.S., is a 31-year-old female presenting with intermittent itchy welts that began 2 days ago.
  • She reports raised, red, itchy areas on her arms, chest, and thighs that appear and disappear within hours.
  • She denies any new medications, foods, insect bites, or personal care products.
  • No fevers, chills, abdominal pain, difficulty breathing, or facial or tongue swelling are reported.

Treatment Considerations

  • The patient's symptoms suggest a possible allergic reaction or skin condition, but the exact cause is unclear.
  • Topical corticosteroids, such as steroid cream, may be considered for treating inflammatory skin conditions 2.
  • However, the patient's symptoms do not clearly indicate a condition that would typically be treated with steroid cream, such as psoriasis or atopic dermatitis.
  • The use of corticosteroids, including steroid cream, can have potential adverse effects, such as skin atrophy, striae, and rosacea, especially with prolonged use or on sensitive skin areas 2, 3, 4.

Decision to Prescribe Steroid Cream

  • Based on the available information, it is unclear whether steroid cream would be an appropriate treatment for K.S.'s symptoms.
  • Further evaluation and diagnosis would be necessary to determine the underlying cause of her symptoms and to consider the potential benefits and risks of treatment with steroid cream.
  • The patient's lack of history with similar symptoms or allergic reactions, and the absence of any clear indication of a condition typically treated with steroid cream, suggest that alternative treatments or further evaluation may be necessary before considering steroid cream 2, 5, 4, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.