What should a doctor do when a 60-year-old patient with diabetes (diabetic) is in a coma due to diabetic ketoacidosis and has a gangrenous foot, but the patient's family refuses a life-saving amputation?

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From the Guidelines

The doctor should proceed with the amputation as it is a life-saving procedure, prioritizing the patient's survival over the family's objections. In this critical situation, where the patient is unconscious and suffering from diabetic ketoacidosis with gangrene, delaying treatment would inevitably lead to fatal septicemia [ 1 ]. The primary ethical obligation of physicians is to act in the best interest of the patient when they cannot make decisions for themselves, adhering to the principles of beneficence (doing good) and non-maleficence (preventing harm).

Key Considerations

  • The patient's condition is life-threatening, and amputation is necessary to prevent the spread of gangrene and subsequent septicemia.
  • The family's concerns, although important, should not override the medical necessity of the procedure in this emergency situation.
  • The doctor should thoroughly document the clinical reasoning, the family's objections, and the decision-making process.
  • After the emergency is addressed, further discussions can be held with the family regarding their cultural and religious concerns about the handling of the amputated limb.

Clinical Guidelines Support

The 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections [ 1 ] emphasizes the importance of prompt and appropriate treatment to prevent the progression of infection and the need for amputations. While this guideline does not directly address the ethical dilemma of family refusal, it underscores the critical nature of timely intervention in cases of severe diabetic foot infections, which aligns with the necessity of proceeding with the amputation in this scenario.

Ethical and Legal Considerations

In real-life clinical practice, the decision to proceed with a life-saving treatment against the family's wishes, especially when the patient is incapable of making their own decisions, is guided by the principle of doing what is in the best interest of the patient. This principle is paramount in emergency situations where delay could result in significant harm or death. The doctor should be prepared to explain the rationale behind the decision to the family, emphasizing the life-saving nature of the intervention and the inevitable outcome of not proceeding with the amputation.

From the Research

Medical Emergency and Treatment

  • The patient is in a coma due to diabetic ketoacidosis and has a gangrenous foot, which is a life-threatening condition 2, 3, 4.
  • The doctors have decided to amputate the foot as soon as the patient is stabilized enough to withstand anesthesia, which is a common treatment for gangrene 5.
  • However, the patient's family is refusing the operation, citing cultural and religious reasons.

Ethical Considerations

  • The doctor is faced with an ethical dilemma, where they must balance the patient's right to life with the family's wishes 6.
  • The patient's condition is critical, and delaying treatment could result in fatal septicemia 3, 4.
  • The doctor must consider the patient's autonomy and best interests, as well as the family's concerns and values.

Possible Courses of Action

  • The doctor could respect the family's wishes and not perform the amputation, which could result in the patient's death 2.
  • The doctor could seek a court order to override the family's decision and perform the amputation, which could be a lengthy and uncertain process.
  • The doctor could report the situation to the authorities, such as a hospital ethics committee, to seek guidance and support 6.
  • The doctor could try to persuade the family to change their decision, by explaining the risks and benefits of the treatment and the potential consequences of not treating the patient 3, 4.
  • The doctor could perform the amputation anyway, citing the patient's best interests and the need to save their life, which could be a controversial and potentially legally risky decision 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Comprehensive review of diabetic ketoacidosis: an update.

Annals of medicine and surgery (2012), 2023

Research

Management of Diabetic Ketoacidosis in Adults: A Narrative Review.

Saudi journal of medicine & medical sciences, 2020

Research

Physiologic amputation: a case study.

Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing, 2014

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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