From the Guidelines
For poison sumac rash, I recommend oral prednisone (typically 40-60mg daily for 5-7 days, tapering down) combined with topical corticosteroids, although the usefulness of over-the-counter topical steroids is uncertain 1. When it comes to managing poison sumac rash, it's crucial to prioritize treatments that reduce morbidity, mortality, and improve quality of life.
- Oral prednisone is a common treatment for poison sumac rash, as it helps reduce the body's inflammatory response to the urushiol oil.
- Topical corticosteroids, such as triamcinolone 0.1% or clobetasol 0.05% cream, may be applied 2-3 times daily to affected areas, despite the uncertainty of their usefulness 1.
- Additionally, cool compresses and oatmeal baths may be considered for relief of local symptoms from exposure to poison sumac 1. It's essential to thoroughly wash the affected area and any potentially contaminated clothing or equipment with soap and water as soon as possible after exposure to remove the plant oil, as recommended by the 2024 American Heart Association and American Red Cross guidelines for first aid 1. If the rash covers more than 10% of your body, affects sensitive areas like your face or genitals, or if you develop fever or difficulty breathing, seek immediate medical attention as these may indicate a severe reaction requiring more intensive treatment.
From the FDA Drug Label
Uses temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: ... poison ivy, oak, sumac ... For a poison sumac rash, oral prednisone may be prescribed, and a suitable topical treatment is hydrocortisone 2.
- Key points:
- Oral prednisone is used to reduce inflammation and itching.
- Topical hydrocortisone is used to relieve itching associated with minor skin irritations and rashes, including those caused by poison sumac.