From the Research
Desonide can be used to treat angular cheilitis, but it should be used cautiously and typically under medical supervision. Desonide is a low-potency topical corticosteroid that helps reduce inflammation and itching. For angular cheilitis, apply a thin layer of desonide cream or ointment (0.05%) to the affected corners of the mouth 2-3 times daily for up to 7-10 days. Avoid applying it to open wounds or infected areas.
Important Considerations
- Since angular cheilitis can be caused by various factors including fungal or bacterial infections, moisture, or nutritional deficiencies, desonide alone may not be sufficient treatment 1.
- If the condition is caused by a fungal infection, an antifungal medication would be more appropriate, such as 1% isoconazole nitrate (ISN) and 0.1% diflucortolone valerate (DFV) ointment, which has been found to be an effective treatment for angular cheilitis 1.
- Prolonged use of corticosteroids like desonide can thin the skin and potentially worsen infections, so it's essential to address the underlying cause of angular cheilitis rather than just treating symptoms.
- Establishing the underlying etiology of AC is required to appropriately focus treatment efforts 2.
Key Points to Keep in Mind
- Angular cheilitis can occur spontaneously but is frequently related to several precipitating factors, such as systemic immune suppression, local irritation, and moisture, fungal and/or bacterial infection 3.
- If symptoms don't improve within a week or worsen, consult a healthcare provider for proper diagnosis and treatment.
- A thorough examination of the oral cavity, other mucosae, and skin is required when managing a cheilitis 3.