What is the cause of a patient's shortness of breath, vomiting, and leg swelling 7 days after an endoscopy?

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Differential Diagnosis

  • Single most likely diagnosis
    • Pulmonary embolism (PE): The patient's symptoms of shortness of breath (SOB), especially when lying down (orthopnea) and on exertion, along with a recent invasive procedure (endoscopy), increase the risk for PE. Although the patient denies chest pain (CP), it's not a universal symptom in PE.
  • Other Likely diagnoses
    • Aspiration pneumonia: Given the patient's recent endoscopy and symptoms of vomiting, cough, and SOB, aspiration pneumonia is a plausible diagnosis. The procedure could have led to aspiration of stomach contents into the lungs.
    • Gastroesophageal reflux disease (GERD) exacerbation: The patient's vomiting and difficulty breathing, especially when lying down, could be related to GERD, which might have been exacerbated by the endoscopy or other factors.
    • Anesthesia-related complications: Although less common, complications from the anesthesia used during the endoscopy, such as respiratory depression or an allergic reaction, could explain the patient's symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cardiac tamponade: Although the patient denies CP, cardiac tamponade can present with SOB, especially when lying down, and could be a complication of the endoscopy if there was accidental puncture of the heart.
    • Pneumothorax: A potential complication of endoscopy, especially if there was an accidental puncture of the lung or esophagus, pneumothorax would require immediate attention.
  • Rare diagnoses
    • Esophageal perforation: A rare but serious complication of endoscopy, esophageal perforation could lead to mediastinitis, abscess formation, and severe infection, presenting with SOB, vomiting, and chest pain.
    • Anaphylaxis: A severe allergic reaction to the anesthesia, medications, or materials used during the endoscopy, anaphylaxis is rare but life-threatening and requires immediate recognition and treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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