What is the treatment for Amyotrophic Lateral Sclerosis (ALS) with Cipro (ciprofloxacin)?

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Last updated: May 7, 2025View editorial policy

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From the Research

Ciprofloxacin (Cipro) is not a treatment for Amyotrophic Lateral Sclerosis (ALS). ALS is a progressive neurodegenerative disease affecting motor neurons, and there is currently no cure. The FDA-approved medications for ALS are riluzole (Rilutek), which may extend survival by 2-3 months, and edaravone (Radicava), which may slow disease progression, as stated in the most recent study 1. Ciprofloxacin is an antibiotic used to treat bacterial infections and has no role in ALS management. ALS treatment focuses on symptom management through a multidisciplinary approach including:

  • Physical therapy
  • Respiratory support
  • Speech therapy
  • Nutritional support Patients with ALS should work with neurologists specializing in neuromuscular disorders to develop an individualized treatment plan. Using antibiotics like ciprofloxacin without a specific infection could lead to unnecessary side effects and antibiotic resistance without providing any benefit for the underlying ALS condition. According to the latest review on ALS therapy 2, the current state of ALS treatment includes medication as well as supportive therapy, and there is ongoing research on biomarkers and genetic testing to improve the classification of ALS patients towards personalized medicine. The most recent study on pharmacotherapy for ALS 1 also highlights the importance of approved and upcoming agents, but ciprofloxacin is not mentioned as a treatment option.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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