What medications are safe for children with sensory processing disorders (SPD)?

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Last updated: May 8, 2025View editorial policy

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From the Guidelines

There are no medications specifically approved for treating sensory issues in children, and a comprehensive approach combining behavioral strategies, sensory-friendly environmental modifications, and occupational therapy is typically the most effective way to address these challenges. When considering medications, it's essential to focus on treating the underlying condition that may be contributing to sensory issues, such as ADHD, autism spectrum disorder, or anxiety disorders. For instance, medications like stimulants (e.g., methylphenidate or amphetamine salts) for ADHD or SSRIs (e.g., fluoxetine) for anxiety might indirectly help with sensory symptoms by improving attention regulation or reducing anxiety 1. However, these medications come with side effects and should only be considered after a thorough evaluation by a developmental pediatrician, child psychiatrist, or neurologist. Some studies, such as the one published in Pediatrics in 2012 1, have explored the use of melatonin in children with autism spectrum disorders, finding it to be a safe and effective treatment for reducing sleep problems, which can sometimes be related to sensory issues. Key considerations for managing sensory issues in children include:

  • Non-medication approaches like occupational therapy and sensory integration therapy
  • Environmental modifications to reduce sensory overload
  • Collaboration with healthcare providers to develop a comprehensive treatment plan
  • Careful evaluation of the potential benefits and risks of medications that may indirectly help with sensory symptoms.

From the Research

Medications for Sensory Issues in Children

There are no specific medications mentioned in the provided studies that are recommended for children with sensory issues. However, the studies discuss various therapies and interventions that may help with sensory processing problems.

Therapies and Interventions

  • Sensory integration therapy: This therapy involves activities that provide vestibular, proprioceptive, auditory, and tactile inputs to help organize the sensory system 2, 3.
  • Sensory-based interventions: These interventions use single-sensory strategies, such as weighted vests or therapy balls, to influence a child's state of arousal 3, 4.
  • Occupational therapy: This therapy may be acceptable as one of the components of a comprehensive treatment plan for children with sensory processing problems 2, 5.
  • Environmental enrichment: This approach may improve nonverbal cognitive skills in children with autism spectrum disorder 6.
  • Massage therapy: This therapy may be effective in reducing behavioral problems in children 4.

Important Considerations

  • There is limited and inconclusive research on the effectiveness of sensory integration therapy and other interventions for children with sensory processing problems 2, 3, 6.
  • Parents should be informed of the limitations of these therapies and interventions, and clinicians should discuss these limitations with families 2.
  • A thorough evaluation should be completed to consider other developmental and behavioral disorders that may be associated with sensory processing problems 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A systematic review of sensory processing interventions for children with autism spectrum disorders.

Autism : the international journal of research and practice, 2015

Research

Sensory-Based Intervention for Children with Behavioral Problems: A Systematic Review.

Journal of autism and developmental disorders, 2015

Research

Using a Multifaceted Approach to Working With Children Who Have Differences in Sensory Processing and Integration.

The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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