From the Research
Vitamin K2 can be used to treat muscle cramps, as evidenced by a recent high-quality study showing its efficacy in reducing the frequency, intensity, and duration of nocturnal leg cramps in older adults. This is based on the most recent and highest quality study available, which demonstrated that vitamin K2 supplementation significantly reduced the frequency, intensity, and duration of nocturnal leg cramps in an older population with good safety 1.
Key Findings
- The study published in JAMA Internal Medicine in 2024 found that vitamin K2 supplementation reduced the mean weekly frequency of cramps by 2.67, with a significant difference between the vitamin K2 and placebo groups 1.
- The study also found that vitamin K2 reduced the severity and duration of muscle cramps, with a more significant mean reduction in NLC severity and duration compared to the placebo group 1.
- No adverse events related to vitamin K2 use were identified in the study, suggesting a good safety profile for vitamin K2 supplementation 1.
Clinical Implications
- Vitamin K2 may be a useful treatment option for patients with muscle cramps, particularly nocturnal leg cramps, as it has been shown to be effective in reducing the frequency, intensity, and duration of these cramps 1.
- However, it is essential to note that the evidence for vitamin K2 in treating muscle cramps is still emerging, and more studies are needed to confirm its efficacy and safety in different populations.
- As with any supplement, patients should consult with their healthcare provider before starting vitamin K2 supplementation, especially if they have underlying medical conditions or are taking medications that may interact with vitamin K2.