What is the cause of a keratinous growth resembling a corn protruding from the skin?

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Differential Diagnosis for "Corn Growing Out of Skin"

  • Single Most Likely Diagnosis
    • Dermatofibroma or keratinous cysts: These are benign skin growths that can sometimes resemble a corn or a small, hard protrusion from the skin. The appearance can be misleading, leading to the description of "corn growing out of skin."
  • Other Likely Diagnoses
    • Warts: Caused by the human papillomavirus (HPV), warts can appear as small, hard growths on the skin and might be mistaken for corns, especially if they are in an unusual location or have an atypical appearance.
    • Calluses or corns: Actual corns (clavus) are thickened areas of skin that can develop due to repeated pressure or friction. They might appear as if something is growing out of the skin, especially if they become large or inflamed.
    • Seborrheic keratoses: These are benign growths that can appear as small, wart-like growths or as larger, more pigmented lesions. They are very common and can sometimes be mistaken for other types of skin growths.
  • Do Not Miss Diagnoses
    • Squamous cell carcinoma: A type of skin cancer that can present as a firm, growing nodule or ulcer. It's crucial to consider this diagnosis to ensure timely treatment if it is present.
    • Basal cell carcinoma: The most common form of skin cancer, which can appear as a growing bump or nodule. Early detection is key for effective treatment.
    • Merkel cell carcinoma: A rare but aggressive form of skin cancer that can appear as a firm, growing nodule. It's essential to consider this in the differential diagnosis due to its potential for rapid growth and metastasis.
  • Rare Diagnoses
    • Cutaneous metastasis: Rarely, cancers from other parts of the body can metastasize to the skin, appearing as new growths. This would be an unusual presentation but is important to consider, especially in patients with a history of cancer.
    • Neurofibromas (in neurofibromatosis type 1): These can appear as soft, fleshy growths on or under the skin and might be described in a way that resembles "corn growing out of skin," especially if they are pedunculated.
    • Epidermal inclusion cysts: While not typically described as growing out of the skin, these cysts can become large and might be mistaken for other types of growths if they become inflamed or infected.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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