What are the signs of septic bursitis and its treatment?

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Last updated: May 8, 2025View editorial policy

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From the Guidelines

Septic bursitis should be suspected when a bursa shows signs of infection including redness, warmth, severe tenderness, significant swelling, fever, and intense pain with movement, and treatment requires prompt medical attention with antibiotics, drainage, and supportive care. The signs of septic bursitis include:

  • Redness and warmth of the affected area
  • Severe tenderness and significant swelling
  • Fever
  • Intense pain with movement Treatment typically involves:
  • Empiric antibiotics that cover Staphylococcus aureus, such as cefazolin 1-2g IV every 8 hours or clindamycin 600-900mg IV every 8 hours for those with penicillin allergy 1
  • Aspiration of the bursa for both diagnosis and therapeutic drainage
  • Resting the affected joint
  • Applying ice to reduce inflammation
  • Taking pain relievers like ibuprofen 400-600mg every 6-8 hours as needed Hospitalization is often required for IV antibiotics, with transition to oral antibiotics for a total 10-14 day course once improvement is seen. Drainage or debridement of the affected area should always be performed, and a 3-4 week course of therapy is suggested 1. It is crucial to note that septic bursitis requires aggressive treatment because the infection can spread to nearby joints or the bloodstream if left untreated, potentially causing sepsis or permanent joint damage.

From the Research

Signs of Septic Bursitis

  • The most frequently involved sites are the olecranon (63%) and prepatellar (27%) bursae 2
  • Staphylococcus aureus is the most common pathogen, responsible for 78% of cases 2 and 80% of cases of superficial septic bursitis 3
  • Skin breakage, trauma, and/or occupational risk factors are significantly associated with infections 2
  • Cellulitis adjacent to the affected bursae is frequent (89%) and often extensive 2
  • Profound edema occurs in 11% of affected limbs 2

Treatment of Septic Bursitis

  • The optimal management includes early recognition and prompt initiation of appropriate antibiotic therapy 4
  • Surgical management may be necessary, and complications can arise from open procedures 4
  • Endoscopic bursectomy may be considered for patients requiring surgical debridement, leading to decreased morbidity in those requiring surgical intervention 4
  • Empiric antibiotics without bursal aspiration may be a reasonable initial approach to ED management of select patients with suspected septic olecranon bursitis 5
  • Ceftriaxone is a consideration for definitive therapy of MSSA infection, with a lower risk of toxicity compared to antistaphylococcal antibiotics 6
  • The management of septic bursitis varies considerably across centers, and controlled trials are needed to establish standardized recommendations regarding antibiotic treatment protocols and the indications of surgery 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Septic bursitis: presentation, treatment and prognosis.

The Journal of rheumatology, 1987

Research

Management of septic bursitis.

Joint bone spine, 2019

Research

Recent developments in septic bursitis.

Current infectious disease reports, 2013

Research

Efficacy of empiric antibiotic management of septic olecranon bursitis without bursal aspiration in emergency department patients.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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