What is the antibiotic treatment for bursitis (inflammation of the bursae)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 31, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Antibiotic treatment for septic bursitis should be initiated empirically, covering Staphylococcus aureus and streptococci, with first-line options including cephalexin or dicloxacillin for 7-10 days, as supported by the most recent study 1.

Key Considerations

  • The most recent study 1 suggests that empiric antibiotics without bursal aspiration may be a reasonable initial approach to ED management of select patients with suspected septic olecranon bursitis.
  • Staphylococcus aureus is the most common cause of septic bursitis, as noted in studies 2 and 3.
  • For patients with MRSA risk factors or penicillin allergy, alternative antibiotics such as clindamycin or trimethoprim-sulfamethoxazole may be considered, as discussed in study 4.

Treatment Approach

  • Empiric antibiotic therapy should be initiated promptly, with adjustment based on culture results when available.
  • Bursal drainage for purulent collections, rest, elevation, and anti-inflammatory medications should accompany antibiotic treatment.
  • Non-septic bursitis (from trauma or overuse) does not require antibiotics and should be treated with rest, ice, compression, and NSAIDs.

Important Notes

  • Clinical improvement should be seen within 48-72 hours; lack of response may indicate resistant organisms, deeper infection, or non-infectious etiology requiring further evaluation.
  • The duration of antibiotic therapy may vary depending on the severity of the infection and the patient's response to treatment, as suggested by study 3.

References

Research

Efficacy of empiric antibiotic management of septic olecranon bursitis without bursal aspiration in emergency department patients.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022

Research

Recent developments in septic bursitis.

Current infectious disease reports, 2013

Research

Treatment of methicillin-resistant Staphylococcus aureus: vancomycin and beyond.

Seminars in respiratory and critical care medicine, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.