Differential Diagnosis for Nodules on Tendons in Palm
- Single most likely diagnosis
- Ganglion cysts: These are the most common lump or mass found on the wrist and are typically seen on the tendons in the palm. They are benign and filled with a jelly-like fluid.
- Other Likely diagnoses
- Giant cell tumors of the tendon sheath: These are benign tumors that can occur on the tendons in the palm, often presenting as a nodule.
- Dupuytren's contracture nodules: While primarily known for causing contracture of the fingers, Dupuytren's disease can start with nodules on the palmar fascia, near tendons.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Sarcomas (e.g., synovial sarcoma): Although rare, these malignant tumors can present as nodules on tendons and have a significant impact on prognosis if not identified early.
- Infections (e.g., mycobacterial or fungal infections): Certain infections can cause nodules on tendons and, if not treated properly, can lead to serious complications.
- Rare diagnoses
- Rheumatoid nodules: While more commonly associated with rheumatoid arthritis and found on the extensor surfaces, in rare cases, these nodules can occur on the palmar aspect of the hand, near tendons.
- Xanthomas: These are rare, benign growths that can occur on tendons due to lipid accumulation, often associated with hyperlipidemia.