What are the interventions and workup for Mobitz Type 1 (Wenckebach) second-degree atrioventricular (AV) block?

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Last updated: May 9, 2025View editorial policy

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From the Guidelines

Mobitz type 1 (Wenckebach) heart block typically requires careful monitoring but often doesn't need immediate intervention if the patient is asymptomatic. For symptomatic patients, the approach should be guided by the presence of symptoms that correlate with atrioventricular block, as recommended in the 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay 1.

Key Considerations

  • The initial workup should include a 12-lead ECG to confirm the diagnosis, looking for progressive PR interval prolongation before a dropped QRS complex.
  • Continuous cardiac monitoring, basic laboratory tests (electrolytes, cardiac enzymes), and evaluation for reversible causes such as medication effects (beta-blockers, calcium channel blockers, digoxin), myocardial ischemia, or electrolyte abnormalities are crucial.
  • Echocardiography may be performed to assess cardiac structure and function, particularly in patients with left ventricular ejection fraction between 36% to 50% and atrioventricular block, where techniques that provide more physiologic ventricular activation (e.g., cardiac resynchronization therapy, His bundle pacing) are preferred to right ventricular pacing to prevent heart failure 1.

Management Approach

  • For asymptomatic patients, careful monitoring is often sufficient, but for symptomatic patients, permanent pacemaker implantation is indicated for persistent symptomatic bradycardia, as it is for patients with acquired second-degree Mobitz type II atrioventricular block, high-grade atrioventricular block, or third-degree atrioventricular block not caused by reversible or physiologic causes 1.
  • In patients with decision-making capacity or their legally defined surrogate, shared decision-making and patient-centered care are endorsed, and treatment decisions are based on the best available evidence and on the patient’s goals of care and preferences 1.
  • Identifying patient populations that will benefit the most from emerging pacing technologies (e.g., His bundle pacing, transcatheter leadless pacing systems) will require further investigation as these modalities are incorporated into clinical practice 1.

From the FDA Drug Label

Atropine also may lessen the degree of partial heart block when vagal activity is an etiologic factor In some patients with complete heart block, the idioventricular rate may be accelerated by atropine; in others, the rate is stabilized. Occasionally a large dose may cause atrioventricular (A-V) block and nodal rhythm. Adequate doses of atropine abolish various types of reflex vagal cardiac slowing or asystole

The intervention for Mobitz Type 1 (also known as Wenckebach) may include atropine to lessen the degree of partial heart block when vagal activity is an etiologic factor. Atropine may help stabilize the heart rate in some patients. However, it is essential to use caution and carefully evaluate the patient's response to atropine, as large doses may cause adverse effects such as atrioventricular (A-V) block and nodal rhythm 2.

  • Key considerations:
    • Atropine may be used to treat Mobitz Type 1 when vagal activity is the cause
    • Careful evaluation of the patient's response to atropine is necessary
    • Large doses of atropine may cause adverse effects
    • Atropine's effect on the heart rate may vary depending on the patient's condition 2

From the Research

Interventions for Mobitz Type 1

  • There are no research papers provided to assist in answering this question regarding interventions for Mobitz Type 1.
  • The study 3 discusses the efficacy of pre-emptive analgesia in a clinical setting for day-case knee arthroscopy, which is not directly relevant to Mobitz Type 1.

Workup for Mobitz Type 1

  • Similarly, there is no information provided in the study 3 that pertains to the workup for Mobitz Type 1.
  • The study 3 focuses on the assessment of pre-emptive local anesthesia in knee arthroscopy, and does not address Mobitz Type 1 or its workup.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A randomized, double-blind trial of pre-emptive local anesthesia in day-case knee arthroscopy.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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