What is the cause of my myalgia (muscle ache)?

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Last updated: May 11, 2025View editorial policy

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Differential Diagnosis for Body Ache

  • Single Most Likely Diagnosis
    • Viral infection (e.g., influenza, upper respiratory tract infection): This is often the most common cause of body aches, especially when accompanied by other symptoms like fever, cough, and fatigue.
  • Other Likely Diagnoses
    • Musculoskeletal strain or injury: Overuse or trauma to muscles and joints can lead to body aches.
    • Fibromyalgia: A chronic condition characterized by widespread muscle pain, fatigue, and tender points.
    • Hypothyroidism: An underactive thyroid gland can cause muscle aches, fatigue, and joint pain.
    • Anemia: A decrease in red blood cells or hemoglobin can lead to fatigue, weakness, and body aches.
  • Do Not Miss Diagnoses
    • Lyme disease: A bacterial infection transmitted by ticks, which can cause body aches, fever, and a characteristic rash.
    • Meningitis: Inflammation of the membranes surrounding the brain and spinal cord, which can cause severe body aches, fever, and stiff neck.
    • Sepsis: A life-threatening condition caused by a severe infection, which can lead to body aches, fever, and organ dysfunction.
    • Multiple myeloma: A type of blood cancer that can cause bone pain, fatigue, and weakness.
  • Rare Diagnoses
    • Polymyalgia rheumatica: An inflammatory condition that causes muscle pain and stiffness, especially in the shoulders and hips.
    • Polymyositis: An inflammatory muscle disease that can cause muscle weakness and pain.
    • Sarcoidosis: A condition that causes inflammation in various parts of the body, including the muscles and joints.
    • Eosinophilia-myalgia syndrome: A rare condition characterized by muscle pain, weakness, and elevated eosinophil counts.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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