Is Vicks (camphor, menthol, and eucalyptus oil) vapor rub effective for treating knee pain?

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Last updated: May 11, 2025View editorial policy

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From the Guidelines

Vicks VapoRub is not a recommended treatment for knee pain, and patients should instead consider using topical capsaicin, which has been shown to have a moderate effect in reducing moderate knee pain associated with osteoarthritis (OA) 1. When considering treatment options for knee pain, it's essential to prioritize evidence-based recommendations that focus on reducing morbidity, mortality, and improving quality of life.

  • Topical capsaicin, which is obtained from chili peppers, works by depleting substance P, a neuropeptide that plays a role in pain pathogenesis and intensity 1.
  • The use of capsaicin may need to be continuous for 2 to 4 weeks before a therapeutic effect is experienced, and adverse events are typically limited to the site of application, including burning or stinging 1.
  • In contrast, Vicks VapoRub is not specifically designed for knee pain, and its ingredients, such as menthol, camphor, and eucalyptus oil, may only provide temporary relief through a counterirritant effect.
  • For persistent or severe knee pain, it's crucial to consult with a healthcare provider for proper diagnosis and treatment, and to consider using medications specifically designed for joint pain, such as NSAIDs (like ibuprofen or naproxen) 1.
  • The American College of Rheumatology recommends a range of nonpharmacologic and pharmacologic therapies for the management of osteoarthritis, including aerobic, aquatic, and/or resistance exercises, weight loss, and topical capsaicin 1.

From the FDA Drug Label

Temporarily relieves minor aches and pains of muscles and joints due to: • simple backache • arthritis • strains • bruises • sprains

Vicks vapor rub contains menthol, which can be used to temporarily relieve minor aches and pains of muscles and joints, including those caused by arthritis. Since knee pain can be a symptom of arthritis, Vicks vapor rub may be used to help relieve knee pain associated with arthritis or other minor aches and pains of muscles and joints 2.

From the Research

Vicks Vapor Rub for Knee Pain

  • There is no direct evidence in the provided studies to support the use of Vicks Vapor Rub for knee pain.
  • However, the studies discuss various treatments for knee pain, including topical analgesics, which Vicks Vapor Rub is a type of.
  • According to 3, topical analgesics such as diclofenac and ketoprofen have been shown to be effective in treating acute and chronic musculoskeletal pain, including knee pain.
  • Additionally, 4 mentions that topical NSAIDs, such as those found in Vicks Vapor Rub, may be useful in treating acute musculoskeletal pain syndromes and show some efficacy in treating hand and knee osteoarthritis.
  • It is essential to note that Vicks Vapor Rub is not specifically mentioned in any of the studies, and its effectiveness for knee pain is not directly addressed.
  • The studies emphasize the importance of using evidence-based treatments for knee pain, and practitioners should consider the available evidence when recommending treatments to patients 5, 6, 7.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Comprehensive Review of Topical Analgesics for Chronic Pain.

Current pain and headache reports, 2021

Research

9. Chronic knee pain.

Pain practice : the official journal of World Institute of Pain, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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