From the Research
Zepbound may contribute to muscle loss, but the provided evidence does not directly address this topic, and therefore, the recommendation is based on general principles of preserving muscle mass during weight loss. To minimize muscle loss while taking Zepbound, it is essential to incorporate regular resistance training at least 2-3 times per week, focusing on major muscle groups with exercises like squats, chest presses, and rows. Ensure adequate protein intake of approximately 1.2-2.0 grams per kilogram of body weight daily, spread throughout the day in 20-30 gram portions. Stay well-hydrated and maintain a moderate calorie deficit of about 500-750 calories below maintenance rather than extreme restriction. Consume a balanced diet with sufficient vitamins and minerals, particularly calcium and vitamin D, as low levels of vitamin D have been associated with various health issues, including hypothyroidism, as seen in studies such as 1 and 2. While the provided studies 1, 2 discuss the relationship between vitamin D deficiency and hypothyroidism, they do not directly address the topic of Zepbound and muscle loss. However, maintaining adequate vitamin D levels is crucial for overall health, and ensuring sufficient intake can help mitigate potential muscle loss. Key strategies to preserve muscle mass include:
- Regular resistance training
- Adequate protein intake
- Moderate calorie deficit
- Balanced diet with sufficient vitamins and minerals
- Regular monitoring of body composition with a healthcare provider. Given the lack of direct evidence on Zepbound and muscle loss, these general principles are recommended to minimize potential muscle loss during weight reduction.