What is the most likely risk factor for a 4-year-old boy with type 1 diabetes mellitus (T1DM), presenting with hyperthermia, sore throat, and refusal to eat, who has a history of diabetic ketoacidosis, inadequate vaccination status, exposure to secondhand smoke, and poor dental hygiene?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 11, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

The most likely risk factor for this patient's current condition is lack of recommended immunizations (option C). The patient presents with symptoms suggestive of a severe sore throat, including fever, refusal to eat, and characteristic positioning, which could be indicative of a bacterial infection such as epiglottitis or streptococcal pharyngitis. Epiglottitis is commonly caused by Haemophilus influenzae type b (Hib), which is preventable through routine childhood vaccinations 1. The history specifically mentions that the patient has had no childhood vaccinations, making him vulnerable to this potentially life-threatening infection. While other factors like obesity, poor dental hygiene, diabetes, and secondhand smoke exposure may contribute to various health issues, the lack of immunizations is the most direct risk factor for infections that could lead to severe sore throat symptoms. This case highlights the importance of adhering to recommended vaccination schedules, as immunizations are crucial for preventing serious infectious diseases, especially in children with underlying conditions like diabetes who may be more susceptible to complications from infections 2, 3. Some key points to consider in the diagnosis and management of streptococcal pharyngitis include:

  • Clinical manifestations such as fever, intense pain in the throat, and enlarged tonsils 1
  • The use of clinical score systems like the Centor score and McIssac score to decide which patients should undergo diagnostic testing 1
  • Microbiologic testing, such as throat culture or rapid antigen detection test, to confirm the diagnosis 2, 3
  • Antimicrobial therapy with oral penicillin V or amoxicillin as the drugs of choice 1 However, the most critical factor in this patient's case is the lack of immunizations, which puts him at risk for vaccine-preventable infections 4.

Related Questions

What are the discharge instructions for a patient diagnosed with strep throat?
Does doxycycline (Doxycycline) provide coverage for Streptococcal (strep) infections?
What is the recommended dosage of Amoxicillin (amoxicillin) for the treatment of streptococcal pharyngitis (strep throat)?
Can Group A beta-hemolytic streptococcal (GABHS) pharyngitis resolve without antibiotic treatment?
Is 100mg twice daily (b.d.) doxycycline an appropriate treatment for streptococcal pharyngitis?
What additional therapy, besides aspirin, would be indicated for a 63-year-old patient with inferior myocardial infarction (MI), normal blood pressure, and elevated Low-Density Lipoprotein (LDL) levels, upon discharge?
What is the most appropriate assessment of the developmental status of a 6-month-old female infant who is at the 40th percentile for length, 50th percentile for weight, and 60th percentile for head circumference, has recently started eating pureed solid foods, squeals but does not babble, and exhibits delayed gross motor skills, including an inability to sit upright without support, pull to stand, or crawl, but has normal cognitive function and fine motor skills, as evidenced by transferring toys and responding to her name?
What is the assessment of this 12-month-old male patient's growth and development?
What screening is recommended for a sexually active 17-year-old female with a history of regular menses, consistent condom use, and previous negative Human Immunodeficiency Virus (HIV), Neisseria gonorrhoeae (gonorrhea), and Chlamydia trachomatis (chlamydia) test results?
What is the most likely underlying diagnosis for an 18-hour-old boy with hypotonia, poor suck reflex, and characteristic physical features, including upslanting palpebral fissures and a protruding tongue, born at approximately 40 weeks gestation to a mother with no prenatal care?
What is the best next step in evaluating a 5-year-old boy with a history of preterm birth (at 30 weeks gestation) and respiratory complications, presenting with significant speech intelligibility issues and a family history of Autism Spectrum Disorder (ASD)?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.