What complication is a 13-day-old, full-term infant with respiratory symptoms, including rhinorrhea, cough, and bilateral wheezes, at greatest risk of developing, given a history of exposure to ill contacts and clinical findings of mild hypothermia (temperature 37.8 degrees Celsius), tachypnea (respirations 70/min), and mild hypoxemia (pulse oximetry 95% on room air)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 12, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

The patient's symptoms of runny nose, cough, fussiness, bilateral wheezes, and crackles, along with a history of exposure to ill children in day care, suggest a respiratory infection. The differential diagnosis can be categorized as follows:

  • Single most likely diagnosis
    • Bronchiolitis: This is the most likely diagnosis given the patient's age, symptoms, and exposure history. Bronchiolitis is a common respiratory illness in infants, often caused by respiratory syncytial virus (RSV), and is characterized by inflammation of the small airways.
  • Other Likely diagnoses
    • Viral pneumonia: The patient's symptoms and physical examination findings, such as bilateral wheezes and crackles, could also be consistent with viral pneumonia.
    • Influenza: Although less common in this age group, influenza should be considered, especially during the winter season.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Apnea: The patient is at risk of developing apnea, especially if the underlying condition is bronchiolitis or another respiratory infection. Apnea can be a life-threatening complication, particularly in young infants.
    • Bacteremia: Although less likely, bacteremia should be considered, especially if the patient's condition worsens or if there are signs of sepsis.
  • Rare diagnoses
    • Congenital heart disease: Although the patient's birth history is unremarkable, congenital heart disease could present with similar symptoms, such as fussiness and respiratory distress.
    • Cystic fibrosis: This is a rare genetic disorder that can present with respiratory symptoms, but it is less likely given the patient's age and lack of other symptoms.

The patient is at greatest risk of developing apnea as a complication, given the symptoms and age of the patient. Apnea is a well-known complication of bronchiolitis and other respiratory infections in young infants, and it requires close monitoring and prompt intervention if it occurs.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.