What are pre-tibial plaques?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 12, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Pre-tibial plaques are not directly mentioned in the provided evidence, but based on the information given, it can be inferred that they might be related to inflammatory skin conditions such as psoriasis or erythema nodosum.

Definition and Causes

Pre-tibial plaques can be thought of as thick, raised patches of skin that appear on the front part of your lower legs, just in front of your shin bones. These patches often look reddish or purplish, feel hard when touched, and can sometimes be itchy or painful. They happen when your body's immune system gets confused and attacks normal skin cells, causing inflammation and extra collagen (a protein in your skin) to build up 1.

Types of Skin Conditions

Psoriasis is a chronic inflammatory skin disease that classically presents with well-demarcated, pink plaques with silvery scale, commonly involving the scalp, elbows, knees, and presacral region, though any area of skin might be involved 1. Erythema nodosum (EN) is another condition that can cause raised, tender, red or violet subcutaneous nodules of 1–5 cm in diameter, commonly affecting the extensor surfaces of the extremities, particularly the anterior tibial areas 1.

Importance of Diagnosis and Treatment

If you notice unusual patches on your shins, it's essential to see a doctor because proper diagnosis and early treatment can help prevent the plaques from getting worse and causing discomfort. Treatment usually involves using strong steroid creams to reduce inflammation, keeping the area moisturized, and treating any underlying conditions 1.

Key Points to Remember

  • Pre-tibial plaques can be related to inflammatory skin conditions such as psoriasis or erythema nodosum.
  • They appear as thick, raised patches of skin on the front part of your lower legs.
  • Treatment involves using strong steroid creams, keeping the area moisturized, and treating any underlying conditions.
  • Proper diagnosis and early treatment are crucial to prevent the plaques from getting worse and causing discomfort.

From the Research

What are Pre-tibial Plaques

Pre-tibial plaques, also known as pretibial myxedema, are a rare autoimmune manifestation of Graves' disease. They can appear as:

  • Diffuse, nonpitting edema of the shins
  • Plaques
  • Nodules
  • Elephantiasis lesions mimicking lymphedema 2 These plaques are usually asymptomatic and have only cosmetic importance, but in some cases, they can cause intense pruritus related to mucin deposition 3.

Characteristics of Pre-tibial Plaques

The lesions are usually characterized by:

  • Indurated plaques most commonly on the anterior legs
  • Accumulation of highly hydrophilic glycosaminoglycans in the dermis
  • Minimal morbidity, but possible intense pruritus
  • Similar clinical presentation to venous leg ulcers, which may lead to under-recognition 3

Treatment of Pre-tibial Plaques

Treatment options for pre-tibial myxedema include:

  • Topical corticosteroids applied under occlusive dressing
  • Intralesional corticosteroid injections
  • Compressive therapy
  • Systemic immunomodulation in severe cases 2, 4, 5 It's worth noting that most cases of thyroid dermopathy do not require any therapy, and in mildly severe symptomatic cases, topical corticosteroids can be beneficial 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Pretibial Myxedema: Case Presentation and Review of Treatment Options.

The international journal of lower extremity wounds, 2014

Research

Pretibial Myxedema Masquerading as a Venous Leg Ulcer.

Wounds : a compendium of clinical research and practice, 2017

Research

Pretibial myxedema: pathophysiology and treatment options.

American journal of clinical dermatology, 2005

Research

Pre-tibial myxedema: treatment with intralesional corticosteroid.

Anais brasileiros de dermatologia, 2015

Related Questions

What is the best course of treatment for a 73-year-old male with +2 pitting edema in the left lower extremity?
What is the appropriate management for a 30-year-old female with nocturnal bilateral feet swelling?
Does a patient with bilateral lower extremity venous insufficiency, as indicated by a Visual Analog Scale (VAS) score of 4/15/25, and a history of edema, require follow-up after a venous ultrasound showed no evidence of deep vein thrombosis (DVT) or superficial thrombus?
What are the next steps for managing persistent bilateral lower leg edema in a 69-year-old female with impaired renal function (GFR 49), diabetes mellitus (DM) with elevated hemoglobin A1c (HbA1c) of 11.9, and currently taking Lantus (insulin glargine) and Lasix (furosemide) 20 mg daily?
What is the diagnosis for a 24-year-old male (M) presenting with foot swelling?
What is the typical length of Operating Room (OR) time for transcatheter mitral valve repair surgery?
What is the optimal dose of minoxidil (Rogaine) for treating androgenetic alopecia in a 70-year-old male?
What is the effect of Metformin (metformin hydrochloride) on ovulation?
Will an abdominal ultrasound examine the gallbladder?
What is the cause of persistent oral ulcers (mouth sores)?
What additional management options are recommended for a 44-year-old male with chronic prostatitis (inflammation of the prostate gland) versus chronic pelvic pain syndrome, with normal computed tomography (CT) abdomen/pelvis and abdominal sonography (Abd sono) findings, normal creatinine (Cr) levels indicating normal renal function, low prostate-specific antigen (PSA) levels, and a normal digital rectal examination (DRE), who has undergone a normal cystoscopy and has been advised on prevention measures including warm sitz bath, Serenoa repens (Sam-Palmetto), physical therapy, and pelvic floor exercises?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.