What is the clinical significance of a patient's complete blood count (CBC) results showing a white blood cell (WBC) count of 5.5 K/μL, red blood cell (RBC) count of 5.28 M/μL, hemoglobin level of 14.9 g/dL, hematocrit of 44.5%, mean corpuscular volume (MCV) of 84 fL, mean corpuscular hemoglobin (MCH) of 28.2 pg, mean corpuscular hemoglobin concentration (MCHC) of 34 g/dL, platelet count of 178 K/μL, red cell distribution width (RDW) of 12.5%, mean platelet volume (MPV) of 9.7 fL, and differential counts including neutrophils (#neut) of 3.1 K/μL, lymphocytes (#lymph) of 1.4 K/μL, monocytes (#mono) of 0.5 K/μL, eosinophils (#eos) of 0.4 K/μL, and basophils (#baso) of 0.0 K/μL, with percentages of neutrophils (%neut) of 57%, lymphocytes (%lymph) of 26%, monocytes (%mono) of 8.9%, eosinophils (%eos) of 8%, and basophils (%baso) of 1%?

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From the Research

The complete blood count (CBC) results show mostly normal values with a few minor abnormalities, and no immediate action is required based on these results. The white blood cell count, red blood cell count, hemoglobin, hematocrit, and platelet counts are all within normal ranges, indicating good overall blood health. The red blood cell indices (MCV, MCH, MCHC) are also normal, suggesting proper red blood cell size and hemoglobin content. There are two slight abnormalities: a low lymphocyte percentage (26% when the normal range is 30-50%) and an elevated eosinophil percentage (8% when the normal range is 1-6%). The elevated eosinophil count could suggest an allergic reaction, parasitic infection, or other inflammatory condition, as discussed in a study on eosinophilia 1. However, since the absolute counts of both lymphocytes and eosinophils remain within normal ranges, these percentage variations are likely not clinically significant. If you're experiencing symptoms like allergies, skin rashes, or respiratory issues, mentioning the elevated eosinophil percentage to your healthcare provider would be appropriate during your next visit, as eosinophils play a role in allergic diseases and immune responses, as noted in a review of eosinophils in health and disease 2. It's also worth considering the role of lymphocytes in allergic disease, as discussed in a study on the role of lymphocytes in allergic disease 3. Overall, the CBC results suggest that there is no cause for concern, but it's always a good idea to discuss any abnormal results with a healthcare provider to determine the best course of action. A study on the approach to patients with eosinophilia provides guidance on evaluating eosinophilia and determining the underlying cause 4, and another study discusses the importance of eosinophils in humoral immunity 5.

References

Research

Eosinophils: Cells known for over 140 years with broad and new functions.

Allergology international : official journal of the Japanese Society of Allergology, 2021

Research

The role of lymphocytes in allergic disease.

The Journal of allergy and clinical immunology, 2000

Research

Approach to Patients with Eosinophilia.

The Medical clinics of North America, 2020

Research

Eosinophils: important players in humoral immunity.

Clinical and experimental immunology, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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