From the Research
The management of Haley-Haley disease is not directly addressed in the provided evidence, however, based on the most recent and highest quality study available, gabapentin is likely a suitable treatment option for neuropathic pain, which may be a symptom of Haley-Haley disease. The provided evidence does not directly address the management of Haley-Haley disease, but rather focuses on the treatment of epilepsy and neuropathic pain.
- The study by 1 found that gabapentin monotherapy is probably as effective as other antiepileptic drugs in controlling seizures, and may have a better side effect profile compared to carbamazepine.
- The study by 2 found that gabapentin and pregabalin are the most effective treatments for central poststroke pain, with gabapentin having the most significant effect.
- The study by 3 found that lamotrigine is clinically better than carbamazepine for time to treatment failure outcomes in patients with partial onset seizures.
- The study by 4 found that the combination of gabapentin or carbamazepine with benfotiamine or cyanocobalamin has a synergistic antiallodynic interaction in neuropathic rats.
- The study by 5 found that gabapentin has a better cognitive profile compared to carbamazepine in healthy senior adults.
Considering the available evidence, gabapentin may be a suitable treatment option for neuropathic pain associated with Haley-Haley disease, due to its efficacy and relatively favorable side effect profile. However, it is essential to note that the management of Haley-Haley disease should be individualized and based on the specific symptoms and needs of each patient.