What is the cause of hyperesthesia over the back and flanks?

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Differential Diagnosis for Increased Skin Sensitivity over Back and Flanks

  • Single most likely diagnosis
    • Shingles (Herpes Zoster): This condition often presents with increased skin sensitivity, pain, or burning sensation over a specific dermatome, which can include the back and flanks. The rash typically follows the distribution of the affected nerve.
  • Other Likely diagnoses
    • Contact Dermatitis: Irritation or allergic reactions to substances like soaps, detergents, or plants can cause skin sensitivity and rashes on the back and flanks.
    • Eczema (Atopic Dermatitis): Characterized by itchy, inflamed skin, eczema can occur anywhere on the body, including the back and flanks, and may cause increased skin sensitivity.
    • Insect Bites or Stings: Reactions to insect bites or stings can lead to localized skin sensitivity, redness, and swelling.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Multiple Myeloma: Although rare, multiple myeloma can cause skin sensitivity due to amyloid deposits or nerve damage. Early detection is crucial for effective treatment.
    • Sickle Cell Disease: In rare cases, sickle cell disease can cause skin sensitivity and pain due to vaso-occlusive crises affecting the skin.
    • Lyme Disease: If left untreated, Lyme disease can lead to neurological and skin manifestations, including sensitivity and rashes.
  • Rare diagnoses
    • Sjögren's Syndrome: An autoimmune disorder that can cause skin sensitivity, dryness, and rashes, although it is more commonly associated with dry eyes and mouth.
    • Mastocytosis: A condition characterized by an accumulation of mast cells in the skin, which can cause skin sensitivity, itching, and flushing.
    • Neurological disorders (e.g., neuropathy, radiculopathy): Certain neurological conditions can cause skin sensitivity due to nerve damage or dysfunction.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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