What is the diagnosis for a 41-year-old male, recently incarcerated, presenting with fatigue, arthralgias, and a skin infestation, which began approximately 10 days ago?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 41-year-old Male with Fatigue, Joint Aches, and Skin Parasites

  • Single most likely diagnosis
    • Delusional parasitosis: This condition is characterized by a fixed, false belief that one is infested with parasites, which could explain the patient's report of widespread white parasites on his skin. The recent incarceration could be a contributing factor to the development of this psychiatric condition due to stress, isolation, or other environmental factors.
  • Other Likely diagnoses
    • Scabies: A highly contagious skin infestation caused by the mite Sarcoptes scabiei, which could lead to severe itching and the perception of parasites on the skin. The patient's symptoms of fatigue and joint aches could be secondary to the discomfort and stress caused by the infestation.
    • Lice or flea infestation: Given the patient's recent incarceration, he may have been exposed to lice or fleas, which could cause skin irritation and the sensation of parasites.
    • Eczema or dermatitis: Skin conditions like eczema or dermatitis could cause itching and skin lesions, potentially leading the patient to misinterpret his symptoms as parasitic infestation.
  • Do Not Miss diagnoses
    • Neurosyphilis: A condition caused by the progression of syphilis to the nervous system, which can present with a wide range of symptoms, including fatigue, joint aches, and dermatological manifestations. It is essential to consider this diagnosis due to its potential severity and the fact that syphilis can be prevalent in incarcerated populations.
    • HIV-related illness: HIV infection can cause a variety of symptoms, including fatigue, joint aches, and skin rashes. Given the patient's recent incarceration, he may be at higher risk for HIV exposure.
    • Lyme disease: Although less likely, Lyme disease can cause fatigue, joint aches, and skin lesions, making it a crucial diagnosis not to miss, especially if the patient has been exposed to ticks.
  • Rare diagnoses
    • Morgellons disease: A rare condition characterized by the presence of fibers or other materials under the skin, which could be perceived as parasites. However, this diagnosis is controversial and not widely accepted in the medical community.
    • Ekbom syndrome: A rare condition also known as delusional parasitosis, but with a more pronounced psychotic component. It is essential to consider this diagnosis, but it is relatively rare and may not be the primary consideration.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.