What is the diagnosis for a patient with a tricuspid valve (TV) showing trivial regurgitation, normal structure, and a tricuspid regurgitation (TR) velocity of 1.2 meters per second (m/s)?

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From the Guidelines

The tricuspid valve function appears normal with no significant pathology requiring intervention, as indicated by trivial regurgitation, normal right atrial pressure, and low pressure gradient across the valve 1. The tricuspid valve assessment shows normal structure with trivial regurgitation and no stenosis.

  • The inferior vena cava (IVC) caliber is 1.3 cm, which is within normal limits, suggesting normal right atrial pressure.
  • This is confirmed by the measured right atrial pressure of 3 mmHg, which is also normal.
  • The tricuspid regurgitation velocity is 1.2 m/s, indicating a low pressure gradient across the valve. Based on these findings,
  • The right ventricular systolic pressure (RVSP) is likely normal, as calculated from the TR velocity using the modified Bernoulli equation (4v²) plus the right atrial pressure, which would approximate 8-9 mmHg.
  • This is well below the threshold for pulmonary hypertension. According to the 2014 AHA/ACC guideline for the management of patients with valvular heart disease,
  • Trivial tricuspid regurgitation is classified as stage A, where the patient is at risk of TR but has no or trace TR, and normal valve anatomy and hemodynamics 1. No specific treatment is needed for the trivial tricuspid regurgitation,
  • As this is a common finding even in healthy individuals and is not hemodynamically significant. Regular cardiac follow-up with routine echocardiography would be appropriate to monitor for any changes over time,
  • As recommended by the European Society of Cardiology guidelines on the management of valvular heart disease 1.

From the Research

Tricuspid Valve Structure and Function

  • The tricuspid valve is a complex structure that can be affected by various diseases, including tricuspid regurgitation and stenosis 2.
  • Tricuspid regurgitation is frequently encountered and is most often secondary in nature, caused by annular dilatation and leaflet tethering from adverse right ventricular remodelling 2.
  • The assessment of tricuspid valve disease requires a comprehensive evaluation, including non-invasive imaging techniques such as echocardiography, MRI, and CT 2, 3.

Tricuspid Regurgitation

  • Tricuspid regurgitation is an independent predictor of death, and its severity can be quantified using echocardiography 4.
  • The mechanism of tricuspid regurgitation can be defined using 3D echocardiography, which provides a detailed visualization of the tricuspid valve anatomy 4.
  • Transcatheter tricuspid valve intervention (TTVI) is a emerging therapy for tricuspid regurgitation, and multimodality imaging plays a crucial role in patient selection, procedure planning, and guiding the procedure 3.

Imaging Techniques

  • 3D echocardiography is a cost-effective imaging modality that can be used to visualize the tricuspid valve anatomy, define the mechanism of tricuspid regurgitation, and measure the size and geometry of the tricuspid annulus 4.
  • Transesophageal echocardiography and fluoroscopy imaging are key for guiding TTVI procedures, and fusion between these two modalities may further enhance the quality of procedure guiding 3.
  • Echocardiographic evaluation is essential for assessing valve function after transcatheter tricuspid valve-in-valve replacement (TVIV) 5.

Treatment Options

  • Tricuspid valve surgery is indicated for patients with severe tricuspid regurgitation, and the threshold for restrictive ring annuloplasty repair of secondary tricuspid regurgitation has decreased over time 2.
  • Novel transcatheter therapies have begun to emerge for the treatment of tricuspid regurgitation in patients who are deemed at high or prohibitive surgical risk 2, 3.
  • TTVI can be categorized into different types, including direct or indirect tricuspid restrictive annuloplasty, direct or indirect restoration of leaflet coaptation, heterotopic tricuspid valve implantation, and transcatheter tricuspid valve replacement 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Imaging for Tricuspid Valve Repair and Replacement.

JACC. Cardiovascular imaging, 2021

Research

3-Dimensional Echocardiography in Imaging the Tricuspid Valve.

JACC. Cardiovascular imaging, 2019

Research

Echocardiographic Evaluation of Patients Undergoing Transcatheter Tricuspid Valve-In-Valve Replacement.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2019

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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