Osteoid Osteoma Differential Diagnosis
The differential diagnosis for osteoid osteoma can be organized into the following categories:
- Single most likely diagnosis
- Osteoblastoma: This is a close differential for osteoid osteoma, as both are benign bone tumors that can present with similar clinical and radiological features. However, osteoblastoma tends to be larger and can have a more aggressive course.
- Other Likely diagnoses
- Stress fracture: Stress fractures can present with similar symptoms to osteoid osteoma, including pain that worsens at night and improves with activity. However, stress fractures typically have a more gradual onset and are associated with a history of repetitive stress or trauma.
- Brodie's abscess: Brodie's abscess is a type of chronic osteomyelitis that can present with similar radiological features to osteoid osteoma, including a well-defined lytic lesion with a sclerotic rim.
- Enchondroma: Enchondroma is a type of benign cartilaginous tumor that can present with similar radiological features to osteoid osteoma, including a well-defined lytic lesion.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Osteosarcoma: Osteosarcoma is a malignant bone tumor that can present with similar symptoms to osteoid osteoma, including pain and a palpable mass. While osteosarcoma is much less common than osteoid osteoma, it is a critical diagnosis to consider due to its aggressive nature and poor prognosis if left untreated.
- Ewing's sarcoma: Ewing's sarcoma is another type of malignant bone tumor that can present with similar symptoms to osteoid osteoma. It is highly aggressive and requires prompt treatment to improve outcomes.
- Rare diagnoses
- Intraosseous ganglion: Intraosseous ganglion is a rare benign lesion that can present with similar radiological features to osteoid osteoma, including a well-defined lytic lesion.
- Chondroblastoma: Chondroblastoma is a rare benign cartilaginous tumor that can present with similar radiological features to osteoid osteoma, including a well-defined lytic lesion.
- Langerhans cell histiocytosis: Langerhans cell histiocytosis is a rare disorder that can present with similar radiological features to osteoid osteoma, including a well-defined lytic lesion.