What is the diagnosis for a patient with a normal mitral valve structure, no stenosis, trivial regurgitation, and a mean pressure gradient of 6 mmHg, and a normal tricuspid valve structure with no stenosis and trivial regurgitation?

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From the Guidelines

The patient's echocardiographic findings indicate normal mitral and tricuspid valve function, with no significant pathology requiring intervention. The mitral valve has a normal structure with a peak velocity of 1.2 m/s, no stenosis, and only trivial regurgitation, as well as a normal mitral valve area of 3.6 cm² and a mean gradient of 2 mmHg 1. The tricuspid valve also appears normal with no stenosis and only trivial regurgitation, which is frequently detected in normal subjects by echocardiography 1. Key findings include:

  • Normal mitral valve structure and function
  • No mitral stenosis, with a peak gradient of 6 mmHg and a mean gradient of 2 mmHg
  • Trivial mitral regurgitation
  • Normal tricuspid valve structure and function
  • No tricuspid stenosis
  • Trivial tricuspid regurgitation with a velocity of 1.2 m/s
  • Normal inferior vena cava (IVC) caliber of 1.3 cm, suggesting normal right atrial pressure estimated at 3 mmHg
  • Normal right ventricular systolic pressure indicated by the tricuspid regurgitation velocity of 1.2 m/s. Given these findings, no intervention is necessary, as both valves are functioning properly with only physiologically insignificant trivial regurgitation.

From the Research

Mitral Valve Analysis

  • The mitral valve structure is reported as normal with a peak velocity of 1.2 m/s, indicating no stenosis 2.
  • The mean pressure gradient is 6 mmHg, and the mitral valve area (MVA) is 3.6 cm², which is within normal limits 2.
  • Trivial regurgitation is noted, which is a common finding in normally functioning mitral valves 2.

Tricuspid Valve Analysis

  • The tricuspid valve structure is reported as normal with no stenosis, and trivial regurgitation is noted 3, 4.
  • The peak velocity of the tricuspid valve is 1.2 m/s, which is within normal limits 2.
  • The presence of trivial tricuspid regurgitation may be a sign of functional tricuspid regurgitation, which can be associated with mitral valve disease 3, 4, 5.

Relationship between Mitral and Tricuspid Valves

  • The tricuspid valve is closely related to the mitral valve in terms of function, and any pathophysiological condition affecting the mitral valve can potentially affect the tricuspid valve 3.
  • Functional tricuspid regurgitation can develop after mitral valve surgery, and its presence is associated with a poorer prognosis 3, 4, 5.
  • The management of tricuspid regurgitation in patients with mitral valve disease is crucial, and timely intervention may be necessary to prevent poor outcomes 5, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Normal and abnormal prosthetic valve function as assessed by Doppler echocardiography.

Journal of the American College of Cardiology, 1986

Research

Tricuspid regurgitation after successful mitral valve surgery.

Interactive cardiovascular and thoracic surgery, 2012

Research

Functional Tricuspid Regurgitation in Mitral Valve Disease.

Seminars in cardiothoracic and vascular anesthesia, 2019

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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