What are the best ways to reduce seborrhea (excessive oil production) in a middle-aged male?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

To reduce oily skin, a middle-aged male should prioritize a skincare routine that incorporates gentle cleansing, oil control, and products containing salicylic acid or glycolic acid, as these ingredients have been shown to effectively regulate sebum production and reduce inflammation 1. When creating a skincare routine, it's essential to consider the following key components:

  • Wash your face twice daily with a gentle foaming cleanser containing salicylic acid (1-2%) or glycolic acid (5-10%) to help control oil production and reduce acne.
  • Apply an oil-free, non-comedogenic moisturizer to help balance the skin's natural moisture barrier without clogging pores.
  • Use oil-absorbing products containing niacinamide (2-5%) or retinol (0.25-0.5%) in the evening to help regulate sebum production and reduce inflammation. Some notable ingredients to consider include:
  • Salicylic acid, which helps to unclog pores and reduce inflammation
  • Glycolic acid, which helps to exfoliate the skin and improve skin texture
  • Niacinamide, which has been shown to improve skin elasticity and reduce inflammation
  • Retinol, which helps to regulate cell turnover and reduce the appearance of fine lines and wrinkles It's also important to note that oily skin in middle age can be caused by a combination of hormonal, genetic, and environmental factors, so addressing these underlying causes through proper skincare and lifestyle changes can significantly improve skin appearance and comfort 1.

From the FDA Drug Label

CLINICAL PHARMACOLOGY Isotretinoin is a retinoid, which when administered in pharmacologic dosages of 0. 5 to 1 mg/kg/day (see DOSAGE AND ADMINISTRATION), inhibits sebaceous gland function and keratinization. The decrease in sebum secretion is temporary and is related to the dose and duration of treatment with isotretinoin, and reflects a reduction in sebaceous gland size and an inhibition of sebaceous gland differentiation.

The best way to reduce oily skin in a middle-aged male, according to the isotretinoin drug label, is to inhibit sebaceous gland function using isotretinoin. This can lead to a reduction in sebum secretion, which is temporary and dependent on the dose and duration of treatment 2.

  • Key points:
    • Isotretinoin inhibits sebaceous gland function
    • Reduction in sebum secretion is temporary
    • Effect is dependent on dose and duration of treatment
    • Isotretinoin should be taken with food to enhance absorption 2

From the Research

Reducing Oily Skin in Middle-Aged Males

To reduce oily skin, several options can be considered:

  • Topical therapies, including retinoids, benzoyl peroxide, and azelaic acid, are effective in treating acne and reducing oily skin 3, 4
  • Combination therapies, such as adapalene and benzoyl peroxide, can be used to target acne vulgaris and reduce oily skin 3, 5
  • Salicylic acid, a topical keratolytic, can be used to treat comedonal acne and reduce oily skin 6
  • Supramolecular salicylic acid, a modified salicylic acid preparation, has been shown to be effective in treating mild to moderate acne and reducing oily skin 7

Treatment Options

Some treatment options for reducing oily skin include:

  • Adapalene gel, which can be used alone or in combination with benzoyl peroxide 3, 5
  • Benzoyl peroxide lotion, which can be used alone or in combination with adapalene 5
  • Salicylic acid, which can be used as a topical keratolytic to treat comedonal acne and reduce oily skin 6
  • Supramolecular salicylic acid cream, which has been shown to be effective in treating mild to moderate acne and reducing oily skin 7

Considerations

When choosing a treatment option, consider the following:

  • The severity of the acne and oily skin 4
  • The patient's age and skin type 4
  • The potential side effects of the treatment, such as erythema, dryness, and burning 5
  • The cost and availability of the treatment 3

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.