What are the findings of a standard unenhanced Computed Tomography (CT) scan of the brain with 5 millimeter slice thickness, which reveals no midline shift, mass, or space-occupying lesion, but a low-density mucus retention cyst in the right sphenoid sinus?

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Differential Diagnosis

The provided CT scan of the brain shows no significant abnormalities, but a low-density mucus retention cyst is noted in the right sphenoid sinus. Based on the findings, the following differential diagnoses can be considered:

  • Single most likely diagnosis
    • Chronic sphenoid sinusitis: The presence of a low-density mucus retention cyst in the right sphenoid sinus suggests chronic inflammation or infection, which is consistent with chronic sphenoid sinusitis.
  • Other Likely diagnoses
    • Acute sphenoid sinusitis: Although the cyst is described as likely chronic, it's possible that the patient has an acute infection that has not yet led to significant complications.
    • Allergic rhinitis: The presence of a mucus retention cyst could be related to allergic rhinitis, which can cause chronic nasal and sinus congestion.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Sphenoid sinus abscess: Although the CT scan does not show significant abnormalities, a sphenoid sinus abscess can be a life-threatening condition if not promptly diagnosed and treated.
    • Cavernous sinus thrombosis: This is a rare but potentially deadly complication of sinusitis, and it's essential to consider it in the differential diagnosis, especially if the patient presents with symptoms such as headache, fever, or cranial nerve deficits.
  • Rare diagnoses
    • Sphenoid sinus tumor: Although rare, it's possible that the mucus retention cyst could be related to a tumor in the sphenoid sinus, such as an adenocarcinoma or a squamous cell carcinoma.
    • Fungal sinusitis: This is a rare condition that can cause chronic sinusitis and formation of a mucus retention cyst, especially in immunocompromised patients.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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