What are the symptoms and treatment options for Hand, Foot, and Mouth Disease (HFMD)?

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Last updated: May 19, 2025View editorial policy

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From the Research

Hand, foot, and mouth disease is a common viral illness primarily affecting young children, caused by enteroviruses, most commonly Coxsackievirus A16, and treatment focuses on symptom management as the disease typically resolves on its own within 7-10 days. For fever and pain, use acetaminophen (Tylenol) at 10-15 mg/kg every 4-6 hours or ibuprofen (Motrin) at 5-10 mg/kg every 6-8 hours, as recommended by 1.

Symptoms and Treatment

  • Stay hydrated by sipping cold fluids and eating soft foods like yogurt or ice cream, which can soothe mouth sores.
  • Avoid spicy, salty, or acidic foods that may irritate sores.
  • Salt water rinses (1/2 teaspoon salt in warm water) can help with mouth discomfort, as suggested by 2.
  • The disease spreads through direct contact with saliva, respiratory droplets, and feces, so practice good hygiene including frequent handwashing and disinfecting commonly touched surfaces.

Prevention and Management

  • Children should stay home from school or daycare until fever subsides and mouth sores heal.
  • While uncomfortable, hand, foot, and mouth disease rarely causes serious complications, with symptoms typically improving within a week as the body's immune system fights off the virus, as noted by 3.
  • In severe cases, intravenous immunoglobulin may be considered for treatment, as recommended by 1.
  • Vaccination of susceptible individuals in high-risk areas and good personal hygiene are important preventative measures to combat the disease, as suggested by 3.

References

Research

Hand, Foot, and Mouth Disease: A Narrative Review.

Recent advances in inflammation & allergy drug discovery, 2022

Research

Hand-Foot-and-Mouth Disease: Rapid Evidence Review.

American family physician, 2019

Research

Hand, foot and mouth disease: current knowledge on clinical manifestations, epidemiology, aetiology and prevention.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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