What is the cause of chronic rhinorrhea in a 24-year-old male since undergoing cleft palate repair surgery 5 years ago?

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Last updated: May 19, 2025View editorial policy

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Differential Diagnosis for Chronic Runny Nose in a 24-Year-Old Male Post-Cleft Palate Surgery

  • Single Most Likely Diagnosis
    • Chronic rhinitis: This is likely due to the altered anatomy and potential scarring from the cleft palate surgery, leading to persistent nasal discharge.
  • Other Likely Diagnoses
    • Allergic rhinitis: The patient may have developed allergies post-surgery, contributing to the chronic runny nose.
    • Nasal septal perforation or deviation: Complications from the cleft palate surgery could have resulted in a deviated septum or perforation, causing chronic nasal discharge.
    • Gastroesophageal reflux disease (GERD): Stomach acid reflux can irritate the nasal passages, leading to chronic rhinitis.
  • Do Not Miss Diagnoses
    • Nasal tumor or cancer: Although rare, a tumor or cancer in the nasal cavity could cause chronic nasal discharge and should not be missed due to the potential severity of the condition.
    • CSF leak: A cerebrospinal fluid leak could occur as a complication of the cleft palate surgery, presenting with chronic clear nasal discharge.
  • Rare Diagnoses
    • Primary ciliary dyskinesia: A rare genetic disorder affecting the cilia in the respiratory tract, leading to chronic respiratory infections and nasal discharge.
    • Wegener's granulomatosis: A rare autoimmune disorder that can cause chronic inflammation and damage to the nasal passages, leading to chronic nasal discharge.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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