From the Research
It is generally not recommended to take GoLYTELY (polyethylene glycol-electrolyte solution) while breastfeeding without consulting your healthcare provider first. Although the medication is minimally absorbed into the bloodstream and limited amounts would pass into breast milk, there is insufficient research specifically on its safety during lactation 1. If you need bowel preparation for a medical procedure while breastfeeding, discuss this with your doctor who may recommend pumping and storing breast milk before taking GoLYTELY, or temporarily suspending breastfeeding for 24-48 hours after taking the medication. The main concern is not toxicity to the infant but rather potential dehydration and electrolyte imbalances in the mother, which could affect milk production. GoLYTELY works by drawing water into the intestines to cleanse the bowel, which can cause significant fluid loss. If you must take this medication while breastfeeding, ensure you stay well-hydrated by drinking extra clear fluids beyond what the preparation instructions require, and watch for signs of dehydration such as excessive thirst, dizziness, or decreased milk supply.
Some key points to consider when taking medications while breastfeeding include:
- The amount of medication that enters breast milk varies based on the maternal serum concentration and the pharmacologic properties of the medication 1
- Prescribers should use current, accurate resources, such as LactMed, to determine the safety of medications during breastfeeding 1
- Most antidepressants are compatible with breastfeeding, but stimulant medications may decrease milk supply 1
- Acetaminophen and ibuprofen are preferred analgesics during lactation 1
It's essential to consult with your healthcare provider before taking any medication while breastfeeding, as they can provide personalized guidance and recommendations based on your specific situation and the latest evidence 2, 3, 4, 5.