From the Research
Do not mix Vyvanse (lisdexamfetamine) and alcohol, as this combination can be dangerous and is strongly advised against. Vyvanse is a stimulant medication used to treat ADHD and binge eating disorder, while alcohol is a depressant. When combined, these substances can mask each other's effects, potentially leading to overconsumption of either or both.
Specific Risks
- Increased heart rate and blood pressure
- Dehydration
- Impaired judgment and coordination
- Increased risk of alcohol poisoning
- Potential liver damage
- Worsened side effects of Vyvanse According to a recent study 1, co-use of alcohol and medication can have serious negative health effects, such as overdose risk and liver damage. The study found that individuals taking alcohol-interactive medications experienced blunted subjective pleasure when drinking, which could lead to increased drinking in an attempt to achieve a desirable state.
Recommendations
If you're prescribed Vyvanse, follow your doctor's instructions carefully and never drink alcohol while taking this medication. If you have concerns about alcohol use while on Vyvanse, consult your healthcare provider for personalized advice. The interaction between Vyvanse and alcohol occurs because Vyvanse affects neurotransmitters like dopamine and norepinephrine, while alcohol impacts GABA and glutamate systems, leading to unpredictable and potentially harmful effects on your central nervous system. As noted in another study 2, patients do not necessarily follow the advice of their healthcare providers, highlighting the importance of clear communication and education on the risks of combining alcohol and medication.