What is the diagnosis for a patient with urinalysis results showing leukocytosis (White Blood Cell count) 6-10/hpf, hematuria (Red Blood Cell count) 3-5/hpf, bacteriuria (bacteria) few, hemoglobinuria (blood urine) trace, and leukocyte esterase trace, along with impaired renal function (eGFR 46) and mild anemia (hemoglobin 13), and normal lipase levels?

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Differential Diagnosis

The patient's urinalysis and laboratory results suggest a urinary tract issue. Here's a categorized differential diagnosis:

  • Single most likely diagnosis
    • Urinary Tract Infection (UTI): The presence of WBCs (6-10/hpf), few bacteria, and trace leukocyte esterase in the urinalysis supports this diagnosis. The patient's symptoms and lab results are consistent with a mild to moderate UTI.
  • Other Likely diagnoses
    • Chronic Kidney Disease (CKD): The elevated creatinine level (1.53) and decreased eGFR (46) indicate impaired kidney function, which may be a contributing factor to the patient's symptoms.
    • Dehydration: The patient's laboratory results do not specifically indicate dehydration, but it could be a contributing factor to the concentrated urine and elevated creatinine level.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Sepsis: Although the patient's CBC shows a relatively normal white blood cell count, the presence of bacteria in the urine and impaired kidney function increases the risk of sepsis, particularly if the infection spreads.
    • Pyelonephritis: The patient's symptoms and laboratory results could be indicative of pyelonephritis, a kidney infection that requires prompt treatment to prevent serious complications.
    • Kidney Stone: The presence of RBCs (3-5/hpf) in the urine could suggest a kidney stone, which may cause obstruction and lead to severe consequences if not addressed.
  • Rare diagnoses
    • Glomerulonephritis: The patient's laboratory results, including the presence of RBCs and WBCs in the urine, could be indicative of glomerulonephritis, an inflammatory kidney disease.
    • Interstitial Nephritis: The patient's elevated creatinine level and decreased eGFR may be suggestive of interstitial nephritis, a condition characterized by inflammation of the kidney tissue.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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