From the Research
Desiccated thyroid is a natural thyroid hormone replacement medication made from dried animal thyroid glands, typically from pigs, and should be considered as a treatment option for hypothyroidism only when synthetic alternatives like levothyroxine are not effective, due to its potential benefits in improving symptoms and quality of life, as suggested by a systematic review published in 2024 1.
Key Characteristics of Desiccated Thyroid
- It contains both T3 (triiodothyronine) and T4 (thyroxine) hormones, along with other thyroid compounds.
- Common brand names include Armour Thyroid, Nature-Throid, and NP Thyroid.
- Dosing typically starts low (around 15-30 mg daily) and is gradually adjusted based on symptoms and blood test results.
Comparison with Synthetic Alternatives
- Unlike synthetic alternatives like levothyroxine that contain only T4, desiccated thyroid provides both main thyroid hormones in a fixed ratio.
- Some patients report feeling better on desiccated thyroid compared to synthetic options, possibly because it more closely mimics the natural thyroid hormone profile, as noted in a study published in 2020 2.
Important Considerations
- Desiccated thyroid products may have more variable hormone content between batches compared to synthetic alternatives.
- Regular blood tests are necessary to monitor thyroid levels and adjust dosage appropriately.
- Side effects can include heart palpitations, anxiety, insomnia, and weight loss if the dose is too high, as reported in a randomized, double-blind, crossover study published in 2013 3.
Recommendation
- Desiccated thyroid should be used with caution and under close medical supervision, due to its potential risks and variable hormone content, and only when the benefits outweigh the risks, as suggested by a review published in 2020 4.