From the Research
Azithromycin typically remains effective for 2 years from the date of manufacture when stored properly in its original packaging. Once the expiration date printed on the package has passed, the medication should not be used as its safety and effectiveness cannot be guaranteed. For liquid azithromycin suspensions, the shelf life is much shorter - generally only 10 days after reconstitution when stored at room temperature, or 5 days if refrigerated, depending on the specific formulation. Proper storage is essential for maintaining potency; azithromycin tablets should be kept at room temperature (between 59-86°F or 15-30°C) in a dry place away from light and moisture. Using expired antibiotics can be dangerous as they may be less effective at treating infections, potentially leading to treatment failure or antibiotic resistance. The chemical structure of azithromycin gradually breaks down over time, which is why manufacturers establish these expiration dates based on stability testing 1. If you have azithromycin that has changed appearance, developed an unusual odor, or is past its expiration date, it should be properly disposed of rather than consumed. Some key points to consider when storing azithromycin include:
- Store at room temperature
- Keep away from light and moisture
- Do not use past expiration date
- Dispose of properly if expired or damaged It's also important to note that azithromycin has a long half-life and excellent tissue penetration, making it effective for a variety of infections 2. However, the potential for increased bacterial resistance and rare cases of cardiac torsades des pointes in patients at risk should be considered when prescribing azithromycin 2.