From the Research
Exposure to AFFF/PFAS from use of firefighting foam may contribute to the development of hypertension (HTN), although definitive causation has not been fully established. The potential link between AFFF/PFAS exposure and HTN is supported by several epidemiological studies that have found associations between higher PFAS blood levels and increased blood pressure or hypertension risk in both occupationally exposed populations, such as firefighters, and the general public 1, 2. The biological mechanism likely involves PFAS disrupting hormonal systems that regulate blood pressure, interfering with kidney function, promoting inflammation, or directly affecting vascular function. Some studies have investigated the levels of PFAS in firefighters' blood serum, with findings indicating elevated levels of PFOS and PFHxS in firefighters exposed to AFFF 3. However, it is essential to note that while these associations exist, the current evidence is largely observational, and more research is needed to confirm the relationship between AFFF/PFAS exposure and HTN. If you have been exposed to AFFF through firefighting activities, it is crucial to inform your healthcare provider about this occupational exposure during medical evaluations. Regular blood pressure monitoring is advisable, and if diagnosed with hypertension, standard treatments would apply regardless of the potential contributing factor of PFAS exposure 4, 5. Key considerations for managing hypertension in individuals with potential AFFF/PFAS exposure include:
- Regular monitoring of blood pressure
- Informing healthcare providers about occupational exposure to AFFF
- Standard treatments for hypertension, which may include medications such as beta-blockers, calcium channel blockers, or angiotensin receptor blockers
- Lifestyle modifications to reduce blood pressure and cardiovascular risk.