What are the key differences between essential tremor (ET) and Parkinsonian tremor?

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Last updated: May 22, 2025View editorial policy

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Differential Diagnosis for Tremor

To distinguish essential tremor from Parkinsonian tremor, consider the following categories:

  • Single most likely diagnosis
    • Essential tremor: This is the most common movement disorder, characterized by a bilateral, symmetric tremor, often affecting the hands, head, or voice. It typically worsens with action and improves with rest.
  • Other Likely diagnoses
    • Parkinson's disease: A neurodegenerative disorder that presents with a resting tremor, bradykinesia, rigidity, and postural instability. The tremor is often asymmetric and pill-rolling in nature.
    • Dystonic tremor: A type of tremor that occurs in conjunction with dystonia, characterized by involuntary muscle contractions and abnormal postures.
    • Enhanced physiological tremor: An exaggerated physiological tremor, often caused by factors such as anxiety, stress, or certain medications.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Wilson's disease: A rare genetic disorder that can cause tremors, ataxia, and other neurological symptoms, as well as liver disease. If left untreated, it can be fatal.
    • Multiple system atrophy: A rare neurodegenerative disorder that can present with tremors, ataxia, and autonomic dysfunction.
  • Rare diagnoses
    • Orthostatic tremor: A rare type of tremor that occurs when standing and is often associated with a feeling of unsteadiness.
    • Neuropathic tremor: A tremor caused by peripheral nerve damage, which can be seen in conditions such as peripheral neuropathy or radiculopathy.
    • Psychogenic tremor: A tremor with a psychological origin, often associated with conversion disorder or factitious disorder.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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