Differential Diagnosis for Painful Nodules on Fingers
- Single most likely diagnosis
- Rheumatoid Arthritis (RA): This is a common condition that often presents with painful nodules on the fingers, particularly on the proximal interphalangeal and metacarpophalangeal joints. The nodules, known as rheumatoid nodules, are a hallmark of the disease.
- Other Likely diagnoses
- Osteoarthritis (OA): While OA is more commonly associated with joint pain and degeneration, some forms, like nodal OA, can present with painful nodules on the fingers, especially on the distal interphalangeal joints.
- Gout: Gouty tophi can form on the fingers, leading to painful nodules. These deposits of uric acid crystals can cause significant pain and inflammation.
- Psoriatic Arthritis (PsA): PsA can cause painful nodules on the fingers, often accompanied by psoriatic skin lesions and nail changes.
- Do Not Miss diagnoses
- Septic Arthritis: Although less common, septic arthritis can present with a painful nodule on a finger if the infection has led to the formation of a septic bursitis or a localized abscess. This condition requires immediate medical attention.
- Ganglion Cyst: A ganglion cyst can sometimes be painful and may be mistaken for a nodule. These cysts are benign but can cause discomfort and may require surgical intervention.
- Rare diagnoses
- Sarcoidosis: This condition can cause granulomatous nodules on the fingers, although it is less common. Sarcoidosis is a systemic disease that can affect multiple organs.
- Multicentric Reticulohistiocytosis: A rare condition characterized by the formation of nodules on the skin, including the fingers, due to the proliferation of histiocytes. It can be associated with systemic symptoms and arthritis.
- Erythema Elevatum Diutinum: A rare skin condition that can cause painful nodules on the fingers, often associated with systemic diseases like HIV or hematological malignancies.