From the Guidelines
Female hair loss can be effectively treated with Platelet-rich fibrin (PRF), which is a safe, easy, time, and cost-effective adjuvant modality for managing androgenetic alopecia. For female pattern hair loss, the treatment approach should prioritize minimizing morbidity, mortality, and improving quality of life.
Treatment Options
- Topical minoxidil (2% or 5% solution) applied twice daily to the scalp is a common first-line treatment, with visible results typically appearing after 3-6 months of consistent use 1.
- Oral minoxidil at low doses (0.25-2.5mg daily) is an alternative option with potentially better compliance.
- Spironolactone (50-200mg daily) can be effective for women with hormonal hair loss by blocking androgen receptors.
- For those with nutritional deficiencies, supplements including iron, vitamin D, zinc, and biotin may help when levels are low.
- Platelet-rich plasma (PRP) injections, administered every 1-3 months for 3-4 sessions, stimulate hair follicles through growth factors, as supported by recent studies 1.
- Low-level laser therapy devices used 3 times weekly for 15-30 minutes can also promote hair growth.
Recent Evidence
Recent studies have shown that PRF appears to be promising as a safe and effective treatment of androgenetic alopecia, and as an adjuvant to hair transplant surgery 1.
Recommendations
A comprehensive approach combining multiple therapies, including PRF, for optimal results is recommended, and patients should expect that most treatments require at least 3-6 months before improvements become noticeable. Identifying and addressing the underlying cause of hair loss is crucial for effective treatment.
From the Research
Treatment Options for Female Hair Loss
- Minoxidil is a commonly used treatment for female pattern hair loss, with studies showing a moderate increase in hair regrowth compared to placebo 2, 3
- Low-level laser therapy (LLLT) has also been identified as a potentially effective treatment for female androgenetic alopecia, although more research is needed to validate its efficacy 3
- Platelet-rich plasma (PRP) is another treatment that has been studied, but its effectiveness for female hair loss is not as well established as it is for male hair loss 3
Diagnosis and Evaluation
- A comprehensive clinical history and physical examination are essential in evaluating the hair loss patient, along with targeted laboratory testing and possibly a scalp biopsy 4, 5
- Identifying the underlying cause of hair loss is crucial in determining the best course of treatment, whether it be stopping the underlying cause, using topical or systemic formulations, or referring to a dermatologist 4, 5
Psychological Impact and Support
- Hair loss can have a significant emotional and psychological impact on patients, affecting their quality of life and self-esteem 2, 6, 4
- Physician support and education are essential in helping patients cope with hair loss, including discussing expected hair changes, treatment options, and realistic outcomes 6, 4