What is the cause of severe pruritus (itching) in the axillary (armpit) area bilaterally, exacerbated by hot weather, and also affecting the anterior cervical (neck) region?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Severe Itching in Armpit Area and Anterior Part of the Neck

Single Most Likely Diagnosis

  • Eczema/Dermatitis: This is a common condition that can cause severe itching, especially in warm and humid environments. The armpits and neck are common areas affected by eczema, and symptoms can worsen with hot weather.

Other Likely Diagnoses

  • Contact Dermatitis: This condition occurs when the skin comes into contact with an allergen or irritant, leading to itching and inflammation. The armpits and neck are prone to contact dermatitis due to friction, sweat, and exposure to potential allergens.
  • Folliculitis: An infection of the hair follicles, often caused by bacteria or fungi, which can lead to itching, redness, and inflammation in the affected areas.
  • Pruritus due to Dry Skin (Xerosis): Dry skin can cause intense itching, especially in areas like the armpits and neck, and can be exacerbated by hot weather.

Do Not Miss Diagnoses

  • Lymphoma: Although rare, lymphoma can cause itching, especially if it involves the skin or lymph nodes in the neck and armpits. It's essential to consider this diagnosis to avoid missing a potentially life-threatening condition.
  • Hyperthyroidism: Some people with hyperthyroidism may experience itching, especially in the neck and armpits, due to increased sweat production and skin sensitivity.
  • Hodgkin Lymphoma: A type of lymphoma that can cause itching, especially in the neck and armpits, due to the involvement of lymph nodes in these areas.

Rare Diagnoses

  • Polycythemia Vera: A rare blood disorder that can cause itching, especially after exposure to warm water or hot weather, due to the release of histamine from abnormal blood cells.
  • Mastocytosis: A condition characterized by an accumulation of mast cells in the skin, which can cause itching, flushing, and other symptoms, especially in response to heat or other triggers.
  • Neurological Disorders (e.g., Multiple Sclerosis, Neuropathy): In some cases, neurological disorders can cause itching sensations in specific areas, including the armpits and neck, although this is relatively rare.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.