Can Hand, Foot, and Mouth Disease (HFMD) affect adults?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Yes, hand, foot, and mouth disease can affect adults, though it's more common in children under 10 years old. Adults can contract the virus through close contact with infected individuals or contaminated surfaces, as stated in the study published in the American Family Physician in 2019 1. When adults get infected, they may experience milder symptoms or be asymptomatic while still being contagious. Typical symptoms include fever, sore throat, painful red blisters in the mouth, and a rash on the hands, feet, and sometimes buttocks.

Treatment and Prevention

Treatment is supportive, focusing on pain relief with acetaminophen or ibuprofen (follow package dosing instructions), staying hydrated, and using saltwater gargles for mouth sores. The illness typically resolves within 7-10 days without specific antiviral treatment, as noted in the study published in the Cleveland Clinic Journal of Medicine in 2014 2. Adults with the disease should practice good hygiene, avoid close contact with others, and stay home from work to prevent spreading the infection.

Key Considerations

Some key points to consider include:

  • The disease can be associated with complications, leading to severe neurological sequelae and, rarely, to death, as highlighted in the European Journal of Clinical Microbiology & Infectious Diseases in 2018 3.
  • People with weakened immune systems may experience more severe symptoms and should consult a healthcare provider if infected.
  • Vaccines able to confer protection against the most common aetiologic agents in a given country have been developed, but simultaneous circulation of more than one causative virus and modification of the molecular epidemiology of infectious agents make preparations based on a single agent relatively inadequate, as discussed in the European Journal of Clinical Microbiology & Infectious Diseases in 2018 3.

Recommendations

The best methods to prevent the spread of hand-foot-and-mouth disease are handwashing and disinfecting potentially contaminated surfaces and fomites, as recommended in the American Family Physician in 2019 1. Adults with the disease should prioritize staying hydrated, practicing good hygiene, and avoiding close contact with others to prevent spreading the infection.

References

Research

Hand-Foot-and-Mouth Disease: Rapid Evidence Review.

American family physician, 2019

Research

Hand, foot and mouth disease: current knowledge on clinical manifestations, epidemiology, aetiology and prevention.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.