From the Guidelines
Miralax is safe for use during breastfeeding, as the active ingredient polyethylene glycol 3350 is minimally absorbed in the mother's digestive tract and negligible amounts pass into breast milk. According to a recent clinical practice update on pregnancy-related gastrointestinal and liver disease, polyethylene glycol–based laxatives, such as Miralax, are considered a treatment option for constipation in pregnant and breastfeeding persons 1. The update highlights that constipation may be experienced by 20%–40% of pregnant persons and can be attributed to physiological, medication, anatomic, dietary, metabolic, and hormonal changes.
When using Miralax, it is essential to follow the standard adult dose of 17 grams (about 1 heaping tablespoon) of powder dissolved in 8 ounces of water, taken once daily for constipation. It is also crucial to drink plenty of fluids throughout the day to prevent dehydration. Other safe options for constipation during breastfeeding include:
- Increasing dietary fiber intake to the recommended daily amount of approximately 30 g/d
- Staying hydrated by consuming an adequate amount of fluids, particularly water
- Regular physical activity to promote regular bowel movements
- Considering bulk-forming agents, such as psyllium husk or methylcellulose, which are safe to administer during pregnancy and breastfeeding due to the lack of systemic absorption 1.
If constipation persists beyond 7 days of treatment or if severe abdominal pain is experienced, it is recommended to consult a healthcare provider for further evaluation and guidance.
From the FDA Drug Label
IF PREGNANT OR BREAST-FEEDING, ask a health professional before use. The FDA drug label does not answer the question.
From the Research
Miralax Safety for Breastfeeding
- There are no direct studies on the safety of Miralax for breastfeeding mothers in the provided evidence.
- However, Miralax is a brand name for polyethylene glycol (PEG), which is an inert, non-absorbable molecule 2.
- Studies have shown that PEG is safe and effective for the treatment of functional constipation in adults and pediatric patients, with great safety and tolerability 2, 3.
- As PEG is not absorbed by the body, it is unlikely to pass into breast milk, suggesting that Miralax may be safe for breastfeeding mothers 2.
- However, it is essential to consult a healthcare professional before taking any medication, including Miralax, while breastfeeding, as they can provide personalized advice and guidance.
Polyethylene Glycol (PEG) Safety
- PEG has been shown to be more efficacious than placebo for the treatment of functional constipation, with great safety and tolerability 2, 3.
- Studies have also compared PEG to other laxatives, such as lactulose, and found it to be more effective 2.
- The use of PEG has been recommended as a first-line treatment for functional constipation in adults and pediatric patients 2, 3.
Fiber Supplementation and Constipation
- Fiber supplementation has been shown to be effective in improving symptoms of chronic constipation in adults 4.
- Psyllium and pectin have been found to have significant effects on improving stool frequency and consistency 4.
- However, the optimal type and regime of fiber supplementation are still unclear, and more research is needed to standardize recommendations 4.