Differential Diagnosis for Endometrium and Uterine Fibroid
- Single most likely diagnosis
- Leiomyoma (Uterine Fibroid) with associated endometrial thickening: This is the most likely diagnosis given the presence of an 18mm anterior uterine fibroid and a homogeneous endometrium measuring 7.5mm. The fibroid could be causing the endometrial thickening due to compression or hormonal effects.
- Other Likely diagnoses
- Adenomyosis: This condition, where endometrial tissue grows into the uterine wall, could also cause endometrial thickening and is often associated with uterine fibroids.
- Endometrial Hyperplasia: This is a condition where the endometrium grows too thick, which could be caused by hormonal imbalances, and is a possible explanation for the 7.5mm endometrial thickness.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Endometrial Cancer: Although less likely, endometrial cancer must be considered, especially if there are risk factors such as postmenopausal bleeding, obesity, or family history of endometrial cancer. The thickened endometrium could be a sign of early cancer.
- Sarcoma: A rare but deadly type of cancer that could arise in the uterus, potentially masquerading as a fibroid or causing endometrial thickening.
- Rare diagnoses
- Endometrial Polyp: A growth in the lining of the uterus, which could cause localized thickening of the endometrium.
- Metastatic Disease to the Uterus: Rarely, cancers from other parts of the body can metastasize to the uterus, potentially causing thickening of the endometrium or mimicking a fibroid.