From the Guidelines
Alprazolam and Dayvigo should not be taken together due to potentially dangerous interactions. Both medications act as central nervous system depressants, and their combined use can lead to excessive sedation, impaired coordination, cognitive impairment, respiratory depression, and in severe cases, loss of consciousness. Alprazolam is a benzodiazepine that enhances the effects of GABA in the brain, while Dayvigo is a sleep medication that works by blocking orexin receptors. When used simultaneously, they can amplify each other's sedative effects. According to a study published in the Annals of Internal Medicine 1, the use of sedative-hypnotics, including benzodiazepines like alprazolam, has been associated with increased risks of memory loss, confusion, disorientation, dizziness, loss of balance, and falls, particularly in older patients. Some key points to consider when taking these medications include:
- Informing your healthcare provider about all medications you're taking
- Never adjusting dosages or stopping either medication without medical supervision
- Exploring alternative treatment options, such as cognitive behavioral therapy for insomnia or non-benzodiazepine anxiety treatments
- Considering different medication combinations with fewer interaction risks It's essential to consult your healthcare provider before making any changes to your medication regimen, as they can help you weigh the benefits and risks of each treatment option and make informed decisions about your care.
From the Research
Alprazolam and Dayvigo Interactions
- There are no direct studies on the interactions between Alprazolam and Dayvigo in the provided evidence.
- However, it is known that Alprazolam is a benzodiazepine with potential for addictive use 2.
- Dayvigo, also known as Lemborexant, is a medication used to treat insomnia disorder, and its efficacy and safety have been studied in subjects with insomnia disorder receiving medications for depression or anxiety symptoms 3.
- Benzodiazepines, such as Alprazolam, have been shown to have a high potential for addiction and withdrawal symptoms, and their use is generally not recommended for long-term treatment of insomnia or anxiety disorders 4, 5.
- Cognitive Behavioral Therapy (CBT) has been shown to be an effective treatment for insomnia and anxiety disorders, and may be a useful alternative to medication 4, 6.