From the Guidelines
For an 89-year-old female, the ideal blood pressure target is generally below 150/90 mmHg, as recommended by the American College of Physicians and the American Academy of Family Physicians 1. This target is based on high-quality evidence that shows treating hypertension in older adults to moderate targets (<150/90 mm Hg) reduces mortality, stroke, and cardiac events 1.
Key Considerations
- The benefits of treating hypertension in older adults apply regardless of whether they have diabetes 1.
- The most consistent and greatest absolute benefit was shown in trials with a higher mean systolic blood pressure at baseline (>160 mm Hg) 1.
- Any additional benefit from aggressive blood pressure control is small, with a lower magnitude of benefit and inconsistent results across outcomes 1.
- A more recent study from 2025 also supports a blood pressure target of <150/90 mmHg for adults aged 80 years or older, with a more lenient target considered for individuals with symptomatic orthostatic hypotension or age ≥85 years 1.
Treatment Approach
- Treatment should start with lifestyle modifications, including reduced sodium intake, regular physical activity as tolerated, and maintaining a healthy weight.
- If medications are needed, begin with a low dose of a single agent, such as amlodipine, lisinopril, or losartan, with gradual titration to avoid side effects.
- Close monitoring is essential as older adults are more susceptible to orthostatic hypotension, falls, and medication side effects.
- Treatment decisions should consider comorbidities, functional status, and quality of life.
- Overly aggressive blood pressure lowering in very elderly patients can lead to dizziness, falls, and reduced organ perfusion, so a more conservative approach is often warranted compared to younger patients.
Monitoring and Follow-up
- Regular blood pressure monitoring at home and follow-up appointments every 1-3 months are recommended to assess treatment efficacy and tolerability.
- The 2024 European Society of Cardiology guidelines also recommend considering a more lenient blood pressure target for individuals with moderate-to-severe frailty or limited life expectancy 1.
From the Research
Ideal Blood Pressure for an 89-year-old Female
- The American College of Cardiology (ACC)/American Heart Association (AHA) 2011 expert consensus document on hypertension in the elderly recommends that the blood pressure be reduced to less than 140/90 mmHg in adults aged 60-79 years and the systolic blood pressure to 140 to 145 mmHg if tolerated in adults aged 80 years and older 2.
- For adults aged 80 years and older, a blood pressure below 150/90 mmHg has been recommended, with a target goal of less than 140/90 mmHg considered in those with diabetes mellitus or chronic kidney disease 2.
- The 2013 Eighth Joint National Committee (JNC 8) guidelines recommend reducing the blood pressure to less than 140/90 mmHg in adults aged 60 years and older with diabetes mellitus or chronic kidney disease, but to less than 150/90 mmHg in adults aged 60 years and older without diabetes mellitus or chronic kidney disease 2.
- However, a more recent review suggests that it is reasonable to target an office systolic blood pressure of less than 130 mmHg in elderly patients with hypertension, with an individualized approach for those who are institutionalized, with high comorbidity burden, or have a short life expectancy 3.
Considerations for Blood Pressure Goals
- The method of blood pressure measurement is extremely important to consider when determining the blood pressure goal, and proper procedures for accurate blood pressure measurement must be followed 3.
- Other factors important to consider may include the patient's comorbidities, frailty, as well as the patient's potential for adverse drug reactions 3.
- Orthostatic hypotension, a decrease in blood pressure of 20 mmHg or more systolic or 10 mmHg or more diastolic within three minutes of standing, should also be considered, as it is associated with a significant increase in cardiovascular risk and falls 4.