Differential Diagnosis for Cat Scratch Fever with Fever, Leukocytosis, and Single Lymph Node Adenopathy
- Single Most Likely Diagnosis
- Cat Scratch Disease (Bartonellosis): This is the most likely diagnosis given the presentation of fever, leukocytosis, and single lymph node adenopathy after a cat scratch. The disease is caused by Bartonella henselae and typically presents with a papule or pustule at the site of the scratch, followed by regional lymphadenopathy.
- Other Likely Diagnoses
- Infectious Mononucleosis: Caused by Epstein-Barr virus, this condition can present with fever, leukocytosis, and lymphadenopathy, although it typically involves multiple lymph node groups.
- Toxoplasmosis: A parasitic infection that can cause lymphadenopathy, fever, and leukocytosis, especially in immunocompromised individuals.
- Lymphogranuloma Venereum: A sexually transmitted infection caused by Chlamydia trachomatis that can present with fever, leukocytosis, and lymphadenopathy, although it typically involves the inguinal lymph nodes.
- Do Not Miss Diagnoses
- Lymphoma: Although less likely, lymphoma can present with lymphadenopathy, fever, and leukocytosis, and is a critical diagnosis not to miss due to its significant implications for treatment and prognosis.
- Tuberculosis: Can cause lymphadenopathy, fever, and leukocytosis, and is a critical diagnosis to consider, especially in immunocompromised individuals or those with exposure history.
- Sarcoidosis: A systemic granulomatous disease that can cause lymphadenopathy, fever, and leukocytosis, and can be life-threatening if not diagnosed and treated properly.
- Rare Diagnoses
- Brucellosis: A zoonotic infection that can cause fever, leukocytosis, and lymphadenopathy, although it is relatively rare and typically associated with exposure to infected animals or their products.
- Tularemia: A bacterial infection caused by Francisella tularensis that can present with fever, leukocytosis, and lymphadenopathy, although it is relatively rare and typically associated with exposure to infected animals or contaminated water.
- Yersiniosis: A bacterial infection caused by Yersinia enterocolitica that can cause fever, leukocytosis, and lymphadenopathy, although it is relatively rare and typically associated with exposure to contaminated food or water.