What is the interpretation of urinalysis results showing hypersthenuria (Specific Gravity 1.017), neutral pH (7.0), yellow urine color, cloudy appearance, positive leukocyte esterase (3+), proteinuria (1+), negative glucose, ketones, occult blood, and bilirubin, positive nitrite, and microscopic examination revealing pyuria (>30 white blood cells per high power field)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Urinalysis Results

The provided urinalysis results indicate an abnormal urine sample with a cloudy appearance, positive nitrite test, and elevated WBC count. Based on these findings, the following differential diagnoses are considered:

  • Single Most Likely Diagnosis
    • Urinary Tract Infection (UTI): The presence of a positive nitrite test, cloudy urine, and elevated WBC count (>30/hpf) strongly suggests a bacterial UTI. The specific gravity and pH levels are within normal limits, which further supports this diagnosis.
  • Other Likely Diagnoses
    • Pyelonephritis: The elevated WBC count and positive nitrite test could also indicate an upper urinary tract infection, such as pyelonephritis. However, additional symptoms like flank pain and fever would be expected.
    • Urethritis: The presence of WBCs in the urine could also suggest urethritis, an inflammation of the urethra. However, this diagnosis would typically be accompanied by symptoms like dysuria and urethral discharge.
  • Do Not Miss Diagnoses
    • Sepsis: Although less likely, the presence of a positive nitrite test and elevated WBC count could indicate a more severe infection, such as sepsis. This diagnosis would require immediate attention and treatment.
    • Kidney Stone: A kidney stone could cause an obstruction, leading to an infection and subsequent positive urinalysis results. This diagnosis would require imaging studies to confirm.
  • Rare Diagnoses
    • Tuberculosis: Although rare, tuberculosis can infect the urinary tract and cause abnormal urinalysis results. This diagnosis would require additional testing, such as a urine culture for TB.
    • Interstitial Nephritis: This condition, often caused by an allergic reaction or certain medications, could lead to an elevated WBC count in the urine. However, additional symptoms like flank pain and hematuria would be expected.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.