From the Guidelines
Delta 8 THC may pose significant cardiac risks, including increased heart rate, elevated blood pressure, and potential arrhythmias, particularly in individuals with pre-existing heart conditions, and therefore, its use should be approached with caution or avoided entirely in such individuals. These effects occur because delta 8 THC, like other cannabinoids, interacts with the endocannabinoid system which influences cardiovascular function 1. The compound can stimulate the sympathetic nervous system, leading to tachycardia (rapid heart rate) and hypertension.
Some key points to consider regarding the cardiac risks of delta 8 THC include:
- Increased heart rate and blood pressure: Delta 8 THC can cause an increase in heart rate and blood pressure, which can be problematic for individuals with pre-existing heart conditions 1.
- Potential arrhythmias: There is a potential risk of arrhythmias associated with delta 8 THC use, particularly in individuals with a history of heart disease or arrhythmias 1.
- Dose-dependent effects: The risk of cardiac effects may be dose-dependent, with higher doses potentially causing more pronounced cardiovascular effects 1.
- Interactions with cardiac medications: Delta 8 THC may interact with cardiac medications, potentially reducing their effectiveness or increasing side effects 1.
Given the limited research on delta 8 THC specifically, a conservative approach is warranted, especially for those with cardiovascular concerns. If you experience chest pain, palpitations, or shortness of breath after using delta 8 THC, seek medical attention immediately. It is essential to prioritize caution and consider the potential cardiac risks associated with delta 8 THC use, particularly in individuals with pre-existing heart conditions.
From the Research
Cardiac Risks of Delta 8 THC
- The current evidence on the cardiac risks of delta 8 THC is limited, with most studies focusing on its psychoactive effects and potential therapeutic benefits 2, 3, 4.
- However, research on the relationship between cannabis and cardiovascular disease suggests that cannabinoids can cause substantial adverse cardiovascular events, including myocardial infarction, cerebrovascular accidents, arrhythmia, and heart failure 5.
- A study on the effects of (-)-11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl in rats found that the compound produced dose-related, long-lasting hypotension and bradycardia, indicating potential cardiovascular effects 6.
- The lack of regulation and quality control in the production and sale of delta 8 THC products raises concerns about their safety and potential cardiovascular risks 3, 4.
- There is a need for further research on the cardiac risks of delta 8 THC, particularly in humans, to better understand its effects on cardiovascular health 2, 4.
Key Findings
- Delta 8 THC can produce physiological and toxicological effects similar to delta 9 THC, including potential cardiovascular risks 3, 6.
- The widespread availability and lack of regulation of delta 8 THC products have led to reports of medical emergencies, including calls to poison control centers and presentations to emergency departments 3, 4.
- Further research is needed to examine the prevalence and consequences of delta 8 THC use, particularly in relation to cardiovascular health 2, 4.