What is onychogryphosis (nail thickening)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Onychogryphosis treatment should prioritize professional nail trimming by a podiatrist, with surgical nail avulsion and phenolization considered for severe cases, to improve quality of life and prevent complications 1.

Overview of Onychogryphosis

Onychogryphosis is a severe nail disorder characterized by extreme thickening, elongation, and curvature of the nail, often resembling a ram's horn or claw. This condition most commonly affects the toenails, particularly the big toe, and develops gradually over time.

Causes and Risk Factors

Onychogryphosis often results from neglected nail care, trauma, peripheral vascular disease, or fungal infections, such as onychomycosis 1. It's particularly common in elderly individuals with limited mobility or poor vision that prevents proper nail care.

Treatment and Management

Treatment typically involves professional nail trimming by a podiatrist using specialized tools. For severe cases, surgical nail avulsion (complete removal) may be necessary, followed by phenolization to prevent regrowth of the deformed nail. Daily foot soaking in warm water with mild soap can help soften the nail before attempting any home maintenance. Patients should apply moisturizer around the nail but avoid the nail fold to prevent infection. Regular podiatric care is essential for management, especially for patients with diabetes or circulation problems who face higher risks of complications 1.

Importance of Treatment

It is essential to treat onychogryphosis, as it can have a significant impact on the quality of life of patients, causing discomfort, difficulty in wearing footwear and walking, cosmetic embarrassment, and lowered self-esteem 1. If left untreated, onychogryphosis can lead to further complications, such as the development of foot ulcers, osteomyelitis, cellulitis, and gangrene in diabetic patients.

Prevention of Recurrence

To prevent recurrence, patients should be advised to wear protective footwear, apply antifungal powders, and keep their nails as short as possible 1. It is also crucial to treat all infected family members simultaneously, as onychomycosis and tinea pedis are contagious.

From the Research

Definition and Characteristics of Onychogryphosis

  • Onychogryphosis is a disorder of nail plate growth characterized by an opaque, yellow-brown thickening of the nail plate with associated gross hyperkeratosis, elongation, and increased curvature 2.
  • The condition can cause pain, secondary complications, and cosmetic concerns, making it a relatively common and important condition 2.
  • Onychogryphosis can be caused by repeated minor trauma to the foot, and it is commonly seen in clinical practice, particularly in older adults 3.

Etiology and Risk Factors

  • Onychogryphosis is often associated with poor personal care, and it can be caused by a variety of factors, including trauma, peripheral circulation disorders, and diseases of the central nervous system 4.
  • The condition can also be associated with self-neglect, homelessness, dementia, old age, and foot abnormalities, such as hallux valgus and elephantiasis 4.
  • Onychogryphosis has been linked to dermatologic conditions, such as psoriasis and onychomycosis, as well as vascular disease, including peripheral vascular disease and venous varices 5.

Diagnosis and Treatment

  • The diagnosis of onychogryphosis can be difficult to identify in the early stages, as hypertrophy of the nail plate is the earliest manifestation, with more classical features appearing later 4.
  • Treatment options for onychogryphosis include surgical procedures, such as total matricectomy, and subcutaneous flap coverage 3.
  • A rational treatment protocol should be based on basic surgical principles, anatomy of the nail bed, and etiological factors, and may involve a combination of surgical and non-surgical approaches 6.

Associated Conditions and Complications

  • Onychogryphosis has been associated with a range of conditions, including psoriasis, onychomycosis, hallux malleus, hallux valgus, peripheral vascular disease, lower extremity ulcers, and type II diabetes mellitus 5.
  • The condition can result in significant morbidity, including pain, paronychia, and onychogryphosis, and can have a significant impact on quality of life 2, 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Onychogryphosis.

Journal of the American Podiatric Medical Association, 2020

Research

A review of management of ingrown toenails and onychogryphosis.

Canadian family physician Medecin de famille canadien, 1988

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.