What is the recommended duration of low-level laser therapy (LLLT) or photobiomodulation (PBM) treatment using red light?

From the Guidelines

Red light therapy duration should be at least 4 hours for optimal treatment outcomes, as evidenced by a complete clearance rate of 73.5% with 4-hour application of 5-aminolevulinic acid (ALA) gel. This is based on the most recent and highest quality study available, which examined data from 4 studies using ALA as the sensitizing agent 1. The study found that the complete clearance rate with 0.5-hour application was significantly lower, at 23.5%, compared to the 4-hour application.

When considering treatment duration, it's essential to prioritize the most effective and evidence-based approach. In this case, the study suggests that longer treatment durations, such as 4 hours, are more effective for achieving optimal outcomes. Some key points to consider when determining treatment duration include:

• The type of photosensitizing compound used, such as ALA or methyl aminolevulinate
• The energy source and power output of the device, measured in mW/cm²
• The specific skin condition being treated, such as actinic keratosis or acne
• The individual's skin type and sensitivity

It's crucial to follow the specific instructions provided with the device and consult a healthcare provider before beginning treatment for any medical condition. Consistency and cumulative treatment are also essential for achieving and maintaining optimal results 1.

From the Research

Red Light Therapy Duration of Treatment

The duration of red light therapy treatment can vary depending on the specific application and desired outcome.

• Treatment duration can range from 10 to 12 minutes per session, with sessions repeated multiple times a week 2, 3.
• The frequency of treatment can also vary, with some studies using a treatment schedule of two sessions per week for 3 months 2.
• The total number of sessions can range from 30 sessions 4 to ongoing treatment until the end of radiotherapy 3.
• Some studies have shown that the effects of red light therapy can last for up to 1 month after stopping treatment 2.

Factors Affecting Treatment Duration

Several factors can affect the duration of red light therapy treatment, including:

• The specific condition being treated, such as skin aging or radioactive dermatitis 2, 3.
• The intensity and wavelength of the red light used 4, 5.
• The individual's skin type and response to treatment 2, 4.
• The desired outcome, such as improved skin quality or reduced fine lines and wrinkles 2, 4.

Variability in Treatment Protocols

There is variability in the treatment protocols used in different studies, including:

• Different wavelengths and intensities of red light 4, 5.
• Different treatment durations and frequencies 2, 3.
• Different methods of application, such as LED masks or handheld devices 2, 6.
• The need for further research to establish standardized treatment protocols 6.